FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2036405336> ?p ?o ?g. }

• W2036405336 endingPage "44" @default.
• W2036405336 startingPage "39" @default.
• W2036405336 abstract "This study investigated the effect of different arginine (Arg) concentrations on adhesion molecule expression on endothelial cells (ECs) and leukocytes and the transendothelial migration of polymorphonuclear neutrophils (PMNs) through ECs stimulated by plasma or peritoneal drain fluid (PDF) from surgical patients. Human umbilical vein ECs (HUVECs) and PMNs from healthy subjects were treated with different concentrations (0, 50, 100, and 1000 μmol/L) of Arg for 24 h. After that, HUVECs were stimulated for 3 h with plasma or PDF from patients who underwent abdominal surgery, and PMNs were allowed to transmigrate through ECs for 2 h. The HUVEC expression of cellular adhesion molecules (CAMs) and integrin (CD11b) and the interleukin (IL) 8 receptor expression on PMNs were measured by flow cytometry. The PMNs transmigrating through ECs were also analyzed. The results showed that CAM and integrin expressions in PDF groups were higher than those in control groups. Among the PDF groups, IL-8 secretions from ECs and PMNs were lower with 100 and 1000 μmol/L Arg than with 0 and 50 μmol/L Arg, and this was consistent with the expression of the IL-8 receptor on PMNs. In addition, CAM expressions on ECs and CD11b expression on PMNs, as well as PMN transmigration, were lower with 100 and 1000 μmol/L Arg than with 0 and 50 μmol/L Arg. The HUVECs stimulated by plasma from surgical patients had similar effects on surface molecule expression as PDF; however, as shown in PDF stimulation, the effects were not so obvious. Inhibition of nitric oxide production results in high CAM and IL-8 expressions comparable with groups with low Arg administration. The results of this in vitro study suggest that ECs and PMNs were activated after patients' plasma or PDF stimulation. A low Arg concentration comparable with catabolic conditions resulted in higher adhesion molecule expression and greater transendothelial migration of neutrophils. Arginine administration at levels similar to or higher than physiological concentrations reduced IL-8 and CAM expression, and PMN transmigration was also decreased after stimulation with plasma or PDF from surgical patients. Inactivation of NO results in high CAM and IL-8 expression. This finding indicated that NO may be an important endogenous inhibitor for EC-PMN interaction and neutrophil transmigration." @default.
• W2036405336 created "2016-06-24" @default.
• W2036405336 creator A5027316847 @default.
• W2036405336 creator A5039388077 @default.
• W2036405336 creator A5039685752 @default.
• W2036405336 creator A5060990393 @default.
• W2036405336 creator A5079854839 @default.
• W2036405336 creator A5085227110 @default.
• W2036405336 date "2007-07-01" @default.
• W2036405336 modified "2023-10-16" @default.
• W2036405336 title "EFFECT OF ARGININE ON CELLULAR ADHESION MOLECULE EXPRESSION AND LEUKOCYTE TRANSMIGRATION IN ENDOTHELIAL CELLS STIMULATED BY BIOLOGICAL FLUID FROM SURGICAL PATIENTS" @default.
• W2036405336 cites W1965972035 @default.
• W2036405336 cites W1966286149 @default.
• W2036405336 cites W1969594534 @default.
• W2036405336 cites W1978201079 @default.
• W2036405336 cites W1995550749 @default.
• W2036405336 cites W2003379945 @default.
• W2036405336 cites W2009559030 @default.
• W2036405336 cites W2013863464 @default.
• W2036405336 cites W2018215649 @default.
• W2036405336 cites W2029491963 @default.
• W2036405336 cites W2034527093 @default.
• W2036405336 cites W2037664321 @default.
• W2036405336 cites W2046201188 @default.
• W2036405336 cites W2063370730 @default.
• W2036405336 cites W2066469962 @default.
• W2036405336 cites W2073861766 @default.
• W2036405336 cites W2078339353 @default.
• W2036405336 cites W2080106074 @default.
• W2036405336 cites W2084267233 @default.
• W2036405336 cites W2086887634 @default.
• W2036405336 cites W2088416182 @default.
• W2036405336 cites W2094980989 @default.
• W2036405336 cites W2096570619 @default.
• W2036405336 cites W2102431819 @default.
• W2036405336 cites W2120525576 @default.
• W2036405336 cites W2120908238 @default.
• W2036405336 cites W2131868847 @default.
• W2036405336 cites W2132595661 @default.
• W2036405336 cites W2156905295 @default.
• W2036405336 cites W2172139851 @default.
• W2036405336 cites W4230693812 @default.
• W2036405336 cites W4235652741 @default.
• W2036405336 cites W4322696895 @default.
• W2036405336 doi "https://doi.org/10.1097/shk.0b013e31802f0190" @default.
• W2036405336 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17483743" @default.
• W2036405336 hasPublicationYear "2007" @default.
• W2036405336 type Work @default.
• W2036405336 sameAs 2036405336 @default.
• W2036405336 citedByCount "16" @default.
• W2036405336 countsByYear W20364053362016 @default.
• W2036405336 countsByYear W20364053362017 @default.
• W2036405336 countsByYear W20364053362020 @default.
• W2036405336 countsByYear W20364053362021 @default.
• W2036405336 countsByYear W20364053362022 @default.
• W2036405336 countsByYear W20364053362023 @default.
• W2036405336 crossrefType "journal-article" @default.
• W2036405336 hasAuthorship W2036405336A5027316847 @default.
• W2036405336 hasAuthorship W2036405336A5039388077 @default.
• W2036405336 hasAuthorship W2036405336A5039685752 @default.
• W2036405336 hasAuthorship W2036405336A5060990393 @default.
• W2036405336 hasAuthorship W2036405336A5079854839 @default.
• W2036405336 hasAuthorship W2036405336A5085227110 @default.
• W2036405336 hasBestOaLocation W20364053361 @default.
• W2036405336 hasConcept C126322002 @default.
• W2036405336 hasConcept C153911025 @default.
• W2036405336 hasConcept C16224149 @default.
• W2036405336 hasConcept C16685009 @default.
• W2036405336 hasConcept C170493617 @default.
• W2036405336 hasConcept C171779818 @default.
• W2036405336 hasConcept C178790620 @default.
• W2036405336 hasConcept C185592680 @default.
• W2036405336 hasConcept C195687474 @default.
• W2036405336 hasConcept C202751555 @default.
• W2036405336 hasConcept C203014093 @default.
• W2036405336 hasConcept C24998067 @default.
• W2036405336 hasConcept C2777411675 @default.
• W2036405336 hasConcept C2909375385 @default.
• W2036405336 hasConcept C519581460 @default.
• W2036405336 hasConcept C53122370 @default.
• W2036405336 hasConcept C553184892 @default.
• W2036405336 hasConcept C55493867 @default.
• W2036405336 hasConcept C62084212 @default.
• W2036405336 hasConcept C71924100 @default.
• W2036405336 hasConcept C84416704 @default.
• W2036405336 hasConcept C86803240 @default.
• W2036405336 hasConceptScore W2036405336C126322002 @default.
• W2036405336 hasConceptScore W2036405336C153911025 @default.
• W2036405336 hasConceptScore W2036405336C16224149 @default.
• W2036405336 hasConceptScore W2036405336C16685009 @default.
• W2036405336 hasConceptScore W2036405336C170493617 @default.
• W2036405336 hasConceptScore W2036405336C171779818 @default.
• W2036405336 hasConceptScore W2036405336C178790620 @default.
• W2036405336 hasConceptScore W2036405336C185592680 @default.
• W2036405336 hasConceptScore W2036405336C195687474 @default.
• W2036405336 hasConceptScore W2036405336C202751555 @default.
• W2036405336 hasConceptScore W2036405336C203014093 @default.
• W2036405336 hasConceptScore W2036405336C24998067 @default.

• next