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- W2036407370 abstract "<i>Aim:</i> It was the aim of this study to develop a simple, effective and reversible model of obstructive jaundice in rats. <i>Material and Method:</i> Totally, 24 rats were divided into 3 groups: the sham group including sham-operated control rats who underwent laparotomy only (n = 8), the common bile duct standard ligation technique (CBD-SL) group including rats with CBD ligation using silk (n = 8), and the CBD new ligation technique (CBD-NL) group consisting of rats with CBD ligation by a new technique (n = 8). After release of the ligations, the CBD-SL group continued as the CBD-SL releasing group, and the CBD-NL group as the CBD-NL releasing group. <i>Results:</i> It was observed that all the CBD ligated rats were both clinically and biochemically jaundiced but they were relieved after reversing the procedure. <i>Conclusion:</i> We present a simple, effective and reliable rat model which is suitable for studies which require a reversal of obstructive jaundice in rats." @default.
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- W2036407370 date "2009-01-01" @default.
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- W2036407370 title "A New Technique for Inducing and Releasing Obstructive Jaundice in Rats" @default.
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- W2036407370 doi "https://doi.org/10.1159/000247061" @default.
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