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• W2036409478 abstract "[reaction: see text] C,D-ring symmetric chlorins 8 were prepared in 47-85% yield, on scales up to several hundred milligrams, by condensation of appropriately substituted bis-formyldihydrodipyrrins 6 and dipyrromethane bis-carboxylic acids 7 in 5% TFA/CH2Cl2 (25 examples). Target chlorins were chosen to systematically probe the effect of lipophilic and hydrophilic substituents on tissue partitioning and cellular membrane penetration in photodynamic therapy (PDT)." @default.
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• W2036409478 date "2006-03-29" @default.
• W2036409478 modified "2023-09-27" @default.
• W2036409478 title "Studies in Chlorin Chemistry. 3. A Practical Synthesis of C,D-Ring Symmetric Chlorins of Potential Utility in Photodynamic Therapy" @default.
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• W2036409478 doi "https://doi.org/10.1021/jo060041z" @default.
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