Matches in SemOpenAlex for { <https://semopenalex.org/work/W2036427873> ?p ?o ?g. }
Showing items 1 to 97 of
97
with 100 items per page.
- W2036427873 endingPage "198" @default.
- W2036427873 startingPage "191" @default.
- W2036427873 abstract "The in vivo disposition of polystyrene microsphere (MS) with the particle size of 50 nm (MS-50) and lecithin-coated MS-50 (LMS-50) after intravenous administration to rats was characterized. While a rapid elimination from the systemic circulation was observed for MS-50, much more prolonged circulating property was observed for LMS-50. In addition, this in vivo disposition property of LMS-50 was suggested to be ascribed to its lower affinity to the liver, which is the determining organ of the in vivo disposition of MS-50. The evaluation of surface hydrophobicity of MS-50 and LMS-50 in buffer solution revealed that the surface of MS-50 is more hydrophobic than that of LMS-50. However, LMS-50 was oppositely found to be more hydrophobic than that of MS-50 in rat serum. The profiles of serum proteins associated with MS-50 and LMS-50 were also examined by sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE). The results showed that the amounts of some adsorbed proteins are greatly different between MS-50 and LMS-50. From these findings, it was suggested that the substantial difference in the in vivo disposition between MS-50 and LMS-50 would not be attributed to the difference in their surface hydrophobicity in the blood, but the difference in the type of serum proteins associated with them." @default.
- W2036427873 created "2016-06-24" @default.
- W2036427873 creator A5019436239 @default.
- W2036427873 creator A5033861263 @default.
- W2036427873 creator A5035791716 @default.
- W2036427873 creator A5082694156 @default.
- W2036427873 creator A5085916499 @default.
- W2036427873 creator A5091642152 @default.
- W2036427873 date "2001-12-01" @default.
- W2036427873 modified "2023-10-10" @default.
- W2036427873 title "Surface hydrophobicity of particles is not necessarily the most important determinant in their in vivo disposition after intravenous administration in rats" @default.
- W2036427873 cites W113791819 @default.
- W2036427873 cites W13293365 @default.
- W2036427873 cites W1775749144 @default.
- W2036427873 cites W1986249683 @default.
- W2036427873 cites W2015582643 @default.
- W2036427873 cites W2029963634 @default.
- W2036427873 cites W2031655205 @default.
- W2036427873 cites W2034186281 @default.
- W2036427873 cites W2045020855 @default.
- W2036427873 cites W2052287240 @default.
- W2036427873 cites W2075738772 @default.
- W2036427873 cites W2078277466 @default.
- W2036427873 cites W2079236889 @default.
- W2036427873 cites W2087526401 @default.
- W2036427873 cites W211065809 @default.
- W2036427873 cites W2124135681 @default.
- W2036427873 cites W266691892 @default.
- W2036427873 doi "https://doi.org/10.1016/s0168-3659(01)00468-0" @default.
- W2036427873 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11733087" @default.
- W2036427873 hasPublicationYear "2001" @default.
- W2036427873 type Work @default.
- W2036427873 sameAs 2036427873 @default.
- W2036427873 citedByCount "41" @default.
- W2036427873 countsByYear W20364278732012 @default.
- W2036427873 countsByYear W20364278732013 @default.
- W2036427873 countsByYear W20364278732014 @default.
- W2036427873 countsByYear W20364278732015 @default.
- W2036427873 countsByYear W20364278732016 @default.
- W2036427873 countsByYear W20364278732021 @default.
- W2036427873 countsByYear W20364278732022 @default.
- W2036427873 crossrefType "journal-article" @default.
- W2036427873 hasAuthorship W2036427873A5019436239 @default.
- W2036427873 hasAuthorship W2036427873A5033861263 @default.
- W2036427873 hasAuthorship W2036427873A5035791716 @default.
- W2036427873 hasAuthorship W2036427873A5082694156 @default.
- W2036427873 hasAuthorship W2036427873A5085916499 @default.
- W2036427873 hasAuthorship W2036427873A5091642152 @default.
- W2036427873 hasConcept C112705442 @default.
- W2036427873 hasConcept C146543888 @default.
- W2036427873 hasConcept C150903083 @default.
- W2036427873 hasConcept C15744967 @default.
- W2036427873 hasConcept C185592680 @default.
- W2036427873 hasConcept C207001950 @default.
- W2036427873 hasConcept C2778913249 @default.
- W2036427873 hasConcept C38022665 @default.
- W2036427873 hasConcept C43617362 @default.
- W2036427873 hasConcept C55493867 @default.
- W2036427873 hasConcept C77805123 @default.
- W2036427873 hasConcept C86803240 @default.
- W2036427873 hasConcept C98274493 @default.
- W2036427873 hasConceptScore W2036427873C112705442 @default.
- W2036427873 hasConceptScore W2036427873C146543888 @default.
- W2036427873 hasConceptScore W2036427873C150903083 @default.
- W2036427873 hasConceptScore W2036427873C15744967 @default.
- W2036427873 hasConceptScore W2036427873C185592680 @default.
- W2036427873 hasConceptScore W2036427873C207001950 @default.
- W2036427873 hasConceptScore W2036427873C2778913249 @default.
- W2036427873 hasConceptScore W2036427873C38022665 @default.
- W2036427873 hasConceptScore W2036427873C43617362 @default.
- W2036427873 hasConceptScore W2036427873C55493867 @default.
- W2036427873 hasConceptScore W2036427873C77805123 @default.
- W2036427873 hasConceptScore W2036427873C86803240 @default.
- W2036427873 hasConceptScore W2036427873C98274493 @default.
- W2036427873 hasFunder F4320320912 @default.
- W2036427873 hasIssue "3" @default.
- W2036427873 hasLocation W20364278731 @default.
- W2036427873 hasLocation W20364278732 @default.
- W2036427873 hasOpenAccess W2036427873 @default.
- W2036427873 hasPrimaryLocation W20364278731 @default.
- W2036427873 hasRelatedWork W2317690671 @default.
- W2036427873 hasRelatedWork W2333161845 @default.
- W2036427873 hasRelatedWork W2351694587 @default.
- W2036427873 hasRelatedWork W2358690230 @default.
- W2036427873 hasRelatedWork W2381082608 @default.
- W2036427873 hasRelatedWork W2386777182 @default.
- W2036427873 hasRelatedWork W2389814931 @default.
- W2036427873 hasRelatedWork W3030108710 @default.
- W2036427873 hasRelatedWork W318688812 @default.
- W2036427873 hasRelatedWork W38514241 @default.
- W2036427873 hasVolume "77" @default.
- W2036427873 isParatext "false" @default.
- W2036427873 isRetracted "false" @default.
- W2036427873 magId "2036427873" @default.
- W2036427873 workType "article" @default.