Matches in SemOpenAlex for { <https://semopenalex.org/work/W2036428419> ?p ?o ?g. }
Showing items 1 to 76 of
76
with 100 items per page.
- W2036428419 abstract "Umbelliprenin is a prenylated compound which belongs to the class of sesquiterpene coumarins. In continuation of our previous in vitro finding [1], we determined to assess the cancer chemopreventive activity of umbelliprenin in vivo by using a two-stage carcinogenesis assay of mouse skin tumors induced by peroxynitrite as an initiator and 12-O-tetradecanoylphorbol-13-acetate (TPA) as a promoter. In this assay, treatment with umbelliprenin along with peroxynitrite/TPA inhibited papilloma formation up to week 9 and the percentage of papilloma bearers was approximately 86.6% at week 20. The average number of papillomas formed per mouse was only 3.9 even at week 20 which was significantly reduced compared to the control group (p<0.05). The results of the in vivo two-stage mouse skin carcinogenesis test revealed that umbelliprenin possessed a pronounced chemopreventive activity and its activity was comparable to that of curcumin, a well-known chemopreventor. Therefore, umbelliprenin might be valuable as a cancer chemopreventive agent." @default.
- W2036428419 created "2016-06-24" @default.
- W2036428419 creator A5025863828 @default.
- W2036428419 creator A5032595344 @default.
- W2036428419 creator A5045570636 @default.
- W2036428419 creator A5071053434 @default.
- W2036428419 date "2009-07-01" @default.
- W2036428419 modified "2023-09-27" @default.
- W2036428419 title "In vivo cancer chemopreventive activity of umbelliprenin" @default.
- W2036428419 doi "https://doi.org/10.1055/s-0029-1234563" @default.
- W2036428419 hasPublicationYear "2009" @default.
- W2036428419 type Work @default.
- W2036428419 sameAs 2036428419 @default.
- W2036428419 citedByCount "0" @default.
- W2036428419 crossrefType "journal-article" @default.
- W2036428419 hasAuthorship W2036428419A5025863828 @default.
- W2036428419 hasAuthorship W2036428419A5032595344 @default.
- W2036428419 hasAuthorship W2036428419A5045570636 @default.
- W2036428419 hasAuthorship W2036428419A5071053434 @default.
- W2036428419 hasConcept C121608353 @default.
- W2036428419 hasConcept C126322002 @default.
- W2036428419 hasConcept C150903083 @default.
- W2036428419 hasConcept C181199279 @default.
- W2036428419 hasConcept C185592680 @default.
- W2036428419 hasConcept C195794163 @default.
- W2036428419 hasConcept C202751555 @default.
- W2036428419 hasConcept C207001950 @default.
- W2036428419 hasConcept C2778250585 @default.
- W2036428419 hasConcept C2778784160 @default.
- W2036428419 hasConcept C2779107934 @default.
- W2036428419 hasConcept C2780795997 @default.
- W2036428419 hasConcept C2909761558 @default.
- W2036428419 hasConcept C502942594 @default.
- W2036428419 hasConcept C55493867 @default.
- W2036428419 hasConcept C555283112 @default.
- W2036428419 hasConcept C71924100 @default.
- W2036428419 hasConcept C86803240 @default.
- W2036428419 hasConcept C98274493 @default.
- W2036428419 hasConceptScore W2036428419C121608353 @default.
- W2036428419 hasConceptScore W2036428419C126322002 @default.
- W2036428419 hasConceptScore W2036428419C150903083 @default.
- W2036428419 hasConceptScore W2036428419C181199279 @default.
- W2036428419 hasConceptScore W2036428419C185592680 @default.
- W2036428419 hasConceptScore W2036428419C195794163 @default.
- W2036428419 hasConceptScore W2036428419C202751555 @default.
- W2036428419 hasConceptScore W2036428419C207001950 @default.
- W2036428419 hasConceptScore W2036428419C2778250585 @default.
- W2036428419 hasConceptScore W2036428419C2778784160 @default.
- W2036428419 hasConceptScore W2036428419C2779107934 @default.
- W2036428419 hasConceptScore W2036428419C2780795997 @default.
- W2036428419 hasConceptScore W2036428419C2909761558 @default.
- W2036428419 hasConceptScore W2036428419C502942594 @default.
- W2036428419 hasConceptScore W2036428419C55493867 @default.
- W2036428419 hasConceptScore W2036428419C555283112 @default.
- W2036428419 hasConceptScore W2036428419C71924100 @default.
- W2036428419 hasConceptScore W2036428419C86803240 @default.
- W2036428419 hasConceptScore W2036428419C98274493 @default.
- W2036428419 hasIssue "09" @default.
- W2036428419 hasLocation W20364284191 @default.
- W2036428419 hasOpenAccess W2036428419 @default.
- W2036428419 hasPrimaryLocation W20364284191 @default.
- W2036428419 hasRelatedWork W2011413959 @default.
- W2036428419 hasRelatedWork W2025128766 @default.
- W2036428419 hasRelatedWork W2064176965 @default.
- W2036428419 hasRelatedWork W2333962281 @default.
- W2036428419 hasRelatedWork W2384674737 @default.
- W2036428419 hasRelatedWork W2394139859 @default.
- W2036428419 hasRelatedWork W2581550607 @default.
- W2036428419 hasRelatedWork W3145816687 @default.
- W2036428419 hasRelatedWork W3149830425 @default.
- W2036428419 hasRelatedWork W4301149094 @default.
- W2036428419 hasVolume "75" @default.
- W2036428419 isParatext "false" @default.
- W2036428419 isRetracted "false" @default.
- W2036428419 magId "2036428419" @default.
- W2036428419 workType "article" @default.