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- W2036441567 abstract "As parasitology does not detect always succesfully leishmania infections, it was attempted worth to investigate the potential use of ELISA for diagnosis of visceral leishmaniasis.Specific antibodies to leishmania were searched in a) 110 healthy controls (infants and children aged 6 months to 14 years), b) 80 children clinically suspected for leishmaniasis. None of the normal children had antileishmania antibodies. In contrast all 40 children with leishmaniasis had antibodies at the time of diagnosis and 2,6 and 12 months after treatment.In 31 patients leish manias were found in the bone marrow smear. In the remaining 9 children the diagnosis was confirmed by immunofluorescence technique,the clinical course and the positive response to specific treatment.The persistence of high antibody titres at 2 and 6 months did not correlate with the severity or the outcome of the disease.The results demonstrate that ELISA ,is a non invasive valuable supplementary method for diagnosis of leishmaniasis." @default.
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- W2036441567 date "1985-10-01" @default.
- W2036441567 modified "2023-09-26" @default.
- W2036441567 title "ENZYME LINKED IMMUNOSORBENTASSAY (ELISA) IN THE VISCERAL LEISHMANIASIS IN CHILDREN" @default.
- W2036441567 doi "https://doi.org/10.1203/00006450-198510000-00205" @default.
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