Matches in SemOpenAlex for { <https://semopenalex.org/work/W2036446459> ?p ?o ?g. }
Showing items 1 to 71 of
71
with 100 items per page.
- W2036446459 endingPage "273" @default.
- W2036446459 startingPage "268" @default.
- W2036446459 abstract "General mathematical equations describing expected blood and urine drug concentrations were derived to analyze riboflavin excretion data after a single large oral dose followed by multiple smaller but equal doses at equal time intervals. The urinary excretion equation was applied to the riboflavin data to obtain the least squares fit using the IBM digital computer, and by this means the absorption and excretion rates were determined. Such calculations can be applied to find the optimum dosage regimen of other drugs for which the kinetic constants are known. The general expressions reduce to all simpler cases already reported in the literature. General mathematical equations describing expected blood and urine drug concentrations were derived to analyze riboflavin excretion data after a single large oral dose followed by multiple smaller but equal doses at equal time intervals. The urinary excretion equation was applied to the riboflavin data to obtain the least squares fit using the IBM digital computer, and by this means the absorption and excretion rates were determined. Such calculations can be applied to find the optimum dosage regimen of other drugs for which the kinetic constants are known. The general expressions reduce to all simpler cases already reported in the literature." @default.
- W2036446459 created "2016-06-24" @default.
- W2036446459 creator A5003619513 @default.
- W2036446459 creator A5005589734 @default.
- W2036446459 creator A5026256307 @default.
- W2036446459 date "1963-03-01" @default.
- W2036446459 modified "2023-09-27" @default.
- W2036446459 title "Multiple Dose Excretion Kinetics" @default.
- W2036446459 cites W149533258 @default.
- W2036446459 cites W2070795819 @default.
- W2036446459 cites W2078377353 @default.
- W2036446459 cites W297371835 @default.
- W2036446459 cites W3176966456 @default.
- W2036446459 cites W4249897955 @default.
- W2036446459 doi "https://doi.org/10.1002/jps.2600520317" @default.
- W2036446459 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/14000530" @default.
- W2036446459 hasPublicationYear "1963" @default.
- W2036446459 type Work @default.
- W2036446459 sameAs 2036446459 @default.
- W2036446459 citedByCount "22" @default.
- W2036446459 countsByYear W20364464592015 @default.
- W2036446459 crossrefType "journal-article" @default.
- W2036446459 hasAuthorship W2036446459A5003619513 @default.
- W2036446459 hasAuthorship W2036446459A5005589734 @default.
- W2036446459 hasAuthorship W2036446459A5026256307 @default.
- W2036446459 hasConcept C10146269 @default.
- W2036446459 hasConcept C112705442 @default.
- W2036446459 hasConcept C121332964 @default.
- W2036446459 hasConcept C125287762 @default.
- W2036446459 hasConcept C185592680 @default.
- W2036446459 hasConcept C24890656 @default.
- W2036446459 hasConcept C2776155809 @default.
- W2036446459 hasConcept C2780026642 @default.
- W2036446459 hasConcept C33923547 @default.
- W2036446459 hasConcept C55493867 @default.
- W2036446459 hasConcept C71924100 @default.
- W2036446459 hasConcept C98274493 @default.
- W2036446459 hasConceptScore W2036446459C10146269 @default.
- W2036446459 hasConceptScore W2036446459C112705442 @default.
- W2036446459 hasConceptScore W2036446459C121332964 @default.
- W2036446459 hasConceptScore W2036446459C125287762 @default.
- W2036446459 hasConceptScore W2036446459C185592680 @default.
- W2036446459 hasConceptScore W2036446459C24890656 @default.
- W2036446459 hasConceptScore W2036446459C2776155809 @default.
- W2036446459 hasConceptScore W2036446459C2780026642 @default.
- W2036446459 hasConceptScore W2036446459C33923547 @default.
- W2036446459 hasConceptScore W2036446459C55493867 @default.
- W2036446459 hasConceptScore W2036446459C71924100 @default.
- W2036446459 hasConceptScore W2036446459C98274493 @default.
- W2036446459 hasIssue "3" @default.
- W2036446459 hasLocation W20364464591 @default.
- W2036446459 hasLocation W20364464592 @default.
- W2036446459 hasOpenAccess W2036446459 @default.
- W2036446459 hasPrimaryLocation W20364464591 @default.
- W2036446459 hasRelatedWork W1964230245 @default.
- W2036446459 hasRelatedWork W1984705561 @default.
- W2036446459 hasRelatedWork W2009246547 @default.
- W2036446459 hasRelatedWork W2024661303 @default.
- W2036446459 hasRelatedWork W233106779 @default.
- W2036446459 hasRelatedWork W2348302343 @default.
- W2036446459 hasRelatedWork W2378109603 @default.
- W2036446459 hasRelatedWork W2413679651 @default.
- W2036446459 hasRelatedWork W2428410074 @default.
- W2036446459 hasRelatedWork W297699154 @default.
- W2036446459 hasVolume "52" @default.
- W2036446459 isParatext "false" @default.
- W2036446459 isRetracted "false" @default.
- W2036446459 magId "2036446459" @default.
- W2036446459 workType "article" @default.