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• W2036451569 abstract "A novel polysaccharide WPS-2-1, with an average molecular weight of 80 kDa, was purified from aqueous extracts of Laminaria japonica. Monosaccharides analysis revealed that WPS-2-1 was composed of mannose, rhamnose and fucose with a molar ratio of 1.0:2.3:1.2. Analysis by periodate oxidation-Smith degradation indicated that WPS-2-1 had a backbone of array by (1 → 4)-glycosidic linkages. Cytotoxicity assay showed that WPS-2-1 presented significantly higher antitumor activities against A375 and BGC823 cells with a dose-dependent manner, and exhibited lower cytotoxicity to vascular smooth muscle cells. The results suggested that WPS-2-1 should be explored as a potential antitumor agent with low toxicity." @default.
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• W2036451569 date "2012-08-01" @default.
• W2036451569 modified "2023-09-28" @default.
• W2036451569 title "Composition and cytotoxicity of a novel polysaccharide from brown alga (Laminaria japonica)" @default.
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• W2036451569 doi "https://doi.org/10.1016/j.carbpol.2012.03.043" @default.
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