Matches in SemOpenAlex for { <https://semopenalex.org/work/W2036475336> ?p ?o ?g. }
- W2036475336 endingPage "133" @default.
- W2036475336 startingPage "133" @default.
- W2036475336 abstract "Levels of circulating homocysteine, vitamin B6, vitamin B12, and folate in different types of open-angle glaucoma Burak Turgut, Murat Kaya, Sermal Arslan, Tamer Demir, Mete Güler, Mehmet Kaan KayaFırat University School of Medicine, Department of Ophthalmology, Elazıg, TurkeyObjective: To compare the levels of plasma homocysteine (Hcy), vitamin B6 (vit-B6), serum vitamin B12 (vit-B12), and folate in healthy individuals and in patients with normal tension glaucoma (NTG), pseudoexfoliative glaucoma (PXG), or primary open-angle glaucoma (POAG).Study design: A prospective controlled trial.Participants and methods: Forty healthy subjects, 48 patients with NTG, 38 patients with PXG, and 34 patients with POAG were included in the study. Those who used vitamin supplements or medications affecting Hcy and vitamin levels were excluded from the study. The levels of Hcy and vit-B6 were measured by High Performance Liquid Chromatography (HPLC). The levels of serum vit-B12 and folic acid were measured by competitive chemiluminescent enzyme immunoassay (CEI). One-way analysis if variance (ANOVA), analysis of covariance (ANCOVA), and the Tukey honestly significant difference test were used for statistical analysis.Results: The mean Hcy level of the PXG group was 15.46 ± 9.27 μmol/L which was significantly higher (P = 0.03) than that of the control group. There were no statistical differences in serum vit-B12 and folate levels among control subjects and NTG, PXG and POAG groups (P > 0.05). It was found that the mean plasma vit-B6 level was significantly higher in subjects with NTG (P = 0.03) and POAG (P = 0.025) versus controls. Mean vit-B6 levels in NTG and POAG were 30.50 ± 11.29 μg/L and 30 ± 12.15 μg/L, respectively.Conclusions: The plasma level of Hcy was found to be increased only in PXG patients and the plasma levels of vit-B6 were found to increase in the NTG and POAG sample groups. Using homocysteine and vit-B6 levels as the determinants of hyperhomocysteinemia still needs further research.Keywords: normal tension glaucoma, pseudoexfoliative glaucoma, primary open-angle glaucoma, homocysteine, vitamin B6" @default.
- W2036475336 created "2016-06-24" @default.
- W2036475336 creator A5031037225 @default.
- W2036475336 creator A5039614451 @default.
- W2036475336 creator A5048631577 @default.
- W2036475336 creator A5059582893 @default.
- W2036475336 creator A5064877997 @default.
- W2036475336 creator A5082093921 @default.
- W2036475336 date "2010-04-01" @default.
- W2036475336 modified "2023-09-29" @default.
- W2036475336 title "Levels of circulating homocysteine, vitamin B6, vitamin B12, and folate in different types of open-angle glaucoma" @default.
- W2036475336 cites W121555785 @default.
- W2036475336 cites W1529699141 @default.
- W2036475336 cites W1557771952 @default.
- W2036475336 cites W1579819961 @default.
- W2036475336 cites W1715777634 @default.
- W2036475336 cites W1756117989 @default.
- W2036475336 cites W193688925 @default.
- W2036475336 cites W1965952143 @default.
- W2036475336 cites W2000764863 @default.
- W2036475336 cites W2007242048 @default.
- W2036475336 cites W2010697494 @default.
- W2036475336 cites W2014878762 @default.
- W2036475336 cites W2020410272 @default.
- W2036475336 cites W2024469837 @default.
- W2036475336 cites W2025530523 @default.
- W2036475336 cites W2026654109 @default.
- W2036475336 cites W2034784349 @default.
- W2036475336 cites W2050482916 @default.
- W2036475336 cites W2051075706 @default.
- W2036475336 cites W2052189640 @default.
- W2036475336 cites W2061610905 @default.
- W2036475336 cites W2061671127 @default.
- W2036475336 cites W2072321594 @default.
- W2036475336 cites W2075505137 @default.
- W2036475336 cites W2086899296 @default.
- W2036475336 cites W2087671815 @default.
- W2036475336 cites W2091302112 @default.
- W2036475336 cites W2099720811 @default.
- W2036475336 cites W2110247026 @default.
- W2036475336 cites W2119633014 @default.
- W2036475336 cites W2124378690 @default.
- W2036475336 cites W2134335381 @default.
- W2036475336 cites W2136411039 @default.
- W2036475336 cites W2148194011 @default.
- W2036475336 cites W2152834405 @default.
- W2036475336 cites W2158475008 @default.
- W2036475336 cites W2165313350 @default.
- W2036475336 cites W2323783182 @default.
- W2036475336 cites W2438889191 @default.
- W2036475336 cites W3139645958 @default.
- W2036475336 doi "https://doi.org/10.2147/cia.s9918" @default.
- W2036475336 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2861848" @default.
- W2036475336 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20458351" @default.
- W2036475336 hasPublicationYear "2010" @default.
- W2036475336 type Work @default.
- W2036475336 sameAs 2036475336 @default.
- W2036475336 citedByCount "42" @default.
- W2036475336 countsByYear W20364753362012 @default.
- W2036475336 countsByYear W20364753362013 @default.
- W2036475336 countsByYear W20364753362014 @default.
- W2036475336 countsByYear W20364753362015 @default.
- W2036475336 countsByYear W20364753362016 @default.
- W2036475336 countsByYear W20364753362017 @default.
- W2036475336 countsByYear W20364753362018 @default.
- W2036475336 countsByYear W20364753362019 @default.
- W2036475336 countsByYear W20364753362020 @default.
- W2036475336 countsByYear W20364753362021 @default.
- W2036475336 countsByYear W20364753362022 @default.
- W2036475336 crossrefType "journal-article" @default.
- W2036475336 hasAuthorship W2036475336A5031037225 @default.
- W2036475336 hasAuthorship W2036475336A5039614451 @default.
- W2036475336 hasAuthorship W2036475336A5048631577 @default.
- W2036475336 hasAuthorship W2036475336A5059582893 @default.
- W2036475336 hasAuthorship W2036475336A5064877997 @default.
- W2036475336 hasAuthorship W2036475336A5082093921 @default.
- W2036475336 hasBestOaLocation W20364753361 @default.
- W2036475336 hasConcept C102959455 @default.
- W2036475336 hasConcept C105795698 @default.
- W2036475336 hasConcept C118487528 @default.
- W2036475336 hasConcept C126322002 @default.
- W2036475336 hasConcept C134018914 @default.
- W2036475336 hasConcept C2776940978 @default.
- W2036475336 hasConcept C2777090595 @default.
- W2036475336 hasConcept C2778527774 @default.
- W2036475336 hasConcept C2779750884 @default.
- W2036475336 hasConcept C2991803831 @default.
- W2036475336 hasConcept C33923547 @default.
- W2036475336 hasConcept C71924100 @default.
- W2036475336 hasConcept C90924648 @default.
- W2036475336 hasConcept C99476002 @default.
- W2036475336 hasConceptScore W2036475336C102959455 @default.
- W2036475336 hasConceptScore W2036475336C105795698 @default.
- W2036475336 hasConceptScore W2036475336C118487528 @default.
- W2036475336 hasConceptScore W2036475336C126322002 @default.
- W2036475336 hasConceptScore W2036475336C134018914 @default.
- W2036475336 hasConceptScore W2036475336C2776940978 @default.
- W2036475336 hasConceptScore W2036475336C2777090595 @default.