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- W2036495822 abstract "Dendritic cell (DC)-mediated immunotherapy has not been as effective as expected for most solid tumors. This study demonstrates immune responses against solid tumors mediated by DCs charged with photodynamic therapy (PDT)-induced tumor lysates, which contain the heat shock protein (HSP) 70. PDT tumor lysate-pulsed DC (PDT-DC) inhibited the growth of mammary EMT6 tumors to a greater extent than freeze/thawed tumor lysate-pulsed DC (FT-DC) or PDT tumor lysates. PDT-DC also showed significant anti-tumor effects against fully-established (i.e., late-stage) solid tumors. Taken together, these results suggest that PDT-DC vaccination is more effective than conventional DC therapy for the treatment of cancers." @default.
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- W2036495822 date "2012-11-01" @default.
- W2036495822 modified "2023-10-15" @default.
- W2036495822 title "Photodynamic therapy-mediated DC immunotherapy is highly effective for the inhibition of established solid tumors" @default.
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- W2036495822 doi "https://doi.org/10.1016/j.canlet.2012.04.024" @default.
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