Matches in SemOpenAlex for { <https://semopenalex.org/work/W2036566192> ?p ?o ?g. }
Showing items 1 to 98 of
98
with 100 items per page.
- W2036566192 endingPage "66" @default.
- W2036566192 startingPage "59" @default.
- W2036566192 abstract "We have recently identified the first mammalian tRNA-specific adenosine deaminase human ADAT1, a member of the ADAR family of RNA editing enzymes. This protein is responsible for the first step of the unique A(37) to m(1)I(37) modification in eukaryotic tRNA(Ala). Here, we present the genomic structure of murine ADAT1 and the functional expression of mADAT1 cDNA. In mouse, as well as in human, ADAT1 is expressed from a single copy gene. The coding region of the mADAT1 gene is spread over nine exons, covering approximately 30kb of genomic DNA and encodes a protein of 499 amino acids. Overall, mADAT1 shares 81% nucleotide homology and 87.5% protein homology with the human ortholog. The recombinant mouse protein is active specifically and with a high efficiency on human tRNA(Ala) in vitro. Its genomic organization is compared to the structures of the sequence-related, pre-mRNA specific adenosine deaminases ADAR1 and ADAR2." @default.
- W2036566192 created "2016-06-24" @default.
- W2036566192 creator A5056156480 @default.
- W2036566192 creator A5057314480 @default.
- W2036566192 creator A5057347305 @default.
- W2036566192 date "2000-02-01" @default.
- W2036566192 modified "2023-09-27" @default.
- W2036566192 title "Sequence, genomic organization and functional expression of the murine tRNA-specific adenosine deaminase ADAT1" @default.
- W2036566192 cites W1995956654 @default.
- W2036566192 cites W2012463423 @default.
- W2036566192 cites W2012652192 @default.
- W2036566192 cites W2014669590 @default.
- W2036566192 cites W2018793883 @default.
- W2036566192 cites W2019028118 @default.
- W2036566192 cites W2028819432 @default.
- W2036566192 cites W2029526949 @default.
- W2036566192 cites W2032946936 @default.
- W2036566192 cites W2036447800 @default.
- W2036566192 cites W2057448231 @default.
- W2036566192 cites W2083443360 @default.
- W2036566192 cites W2103289600 @default.
- W2036566192 cites W2115149771 @default.
- W2036566192 cites W2117696576 @default.
- W2036566192 cites W2133435396 @default.
- W2036566192 doi "https://doi.org/10.1016/s0378-1119(99)00562-4" @default.
- W2036566192 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10675613" @default.
- W2036566192 hasPublicationYear "2000" @default.
- W2036566192 type Work @default.
- W2036566192 sameAs 2036566192 @default.
- W2036566192 citedByCount "22" @default.
- W2036566192 countsByYear W20365661922013 @default.
- W2036566192 countsByYear W20365661922016 @default.
- W2036566192 countsByYear W20365661922017 @default.
- W2036566192 countsByYear W20365661922021 @default.
- W2036566192 countsByYear W20365661922022 @default.
- W2036566192 countsByYear W20365661922023 @default.
- W2036566192 crossrefType "journal-article" @default.
- W2036566192 hasAuthorship W2036566192A5056156480 @default.
- W2036566192 hasAuthorship W2036566192A5057314480 @default.
- W2036566192 hasAuthorship W2036566192A5057347305 @default.
- W2036566192 hasConcept C104317684 @default.
- W2036566192 hasConcept C153911025 @default.
- W2036566192 hasConcept C153957851 @default.
- W2036566192 hasConcept C165525559 @default.
- W2036566192 hasConcept C17757408 @default.
- W2036566192 hasConcept C187882448 @default.
- W2036566192 hasConcept C21786251 @default.
- W2036566192 hasConcept C2776991684 @default.
- W2036566192 hasConcept C2778323267 @default.
- W2036566192 hasConcept C34628245 @default.
- W2036566192 hasConcept C36823959 @default.
- W2036566192 hasConcept C54355233 @default.
- W2036566192 hasConcept C55493867 @default.
- W2036566192 hasConcept C67705224 @default.
- W2036566192 hasConcept C84148353 @default.
- W2036566192 hasConcept C86803240 @default.
- W2036566192 hasConcept C91779695 @default.
- W2036566192 hasConcept C94671646 @default.
- W2036566192 hasConceptScore W2036566192C104317684 @default.
- W2036566192 hasConceptScore W2036566192C153911025 @default.
- W2036566192 hasConceptScore W2036566192C153957851 @default.
- W2036566192 hasConceptScore W2036566192C165525559 @default.
- W2036566192 hasConceptScore W2036566192C17757408 @default.
- W2036566192 hasConceptScore W2036566192C187882448 @default.
- W2036566192 hasConceptScore W2036566192C21786251 @default.
- W2036566192 hasConceptScore W2036566192C2776991684 @default.
- W2036566192 hasConceptScore W2036566192C2778323267 @default.
- W2036566192 hasConceptScore W2036566192C34628245 @default.
- W2036566192 hasConceptScore W2036566192C36823959 @default.
- W2036566192 hasConceptScore W2036566192C54355233 @default.
- W2036566192 hasConceptScore W2036566192C55493867 @default.
- W2036566192 hasConceptScore W2036566192C67705224 @default.
- W2036566192 hasConceptScore W2036566192C84148353 @default.
- W2036566192 hasConceptScore W2036566192C86803240 @default.
- W2036566192 hasConceptScore W2036566192C91779695 @default.
- W2036566192 hasConceptScore W2036566192C94671646 @default.
- W2036566192 hasIssue "1-2" @default.
- W2036566192 hasLocation W20365661921 @default.
- W2036566192 hasLocation W20365661922 @default.
- W2036566192 hasOpenAccess W2036566192 @default.
- W2036566192 hasPrimaryLocation W20365661921 @default.
- W2036566192 hasRelatedWork W1534608728 @default.
- W2036566192 hasRelatedWork W1968511762 @default.
- W2036566192 hasRelatedWork W1980617967 @default.
- W2036566192 hasRelatedWork W2024055869 @default.
- W2036566192 hasRelatedWork W2038045079 @default.
- W2036566192 hasRelatedWork W2045313050 @default.
- W2036566192 hasRelatedWork W2046089186 @default.
- W2036566192 hasRelatedWork W2048861111 @default.
- W2036566192 hasRelatedWork W2066856346 @default.
- W2036566192 hasRelatedWork W2082941385 @default.
- W2036566192 hasVolume "243" @default.
- W2036566192 isParatext "false" @default.
- W2036566192 isRetracted "false" @default.
- W2036566192 magId "2036566192" @default.
- W2036566192 workType "article" @default.