Matches in SemOpenAlex for { <https://semopenalex.org/work/W2036616773> ?p ?o ?g. }
- W2036616773 endingPage "1078" @default.
- W2036616773 startingPage "1070" @default.
- W2036616773 abstract "Previous studies suggest individuals born with oral clefts and their families have a higher susceptibility for cancer, which raises the hypothesis that these two conditions share common molecular pathways. This study evaluated the association between oral clefts and polymorphisms in genes that play a role in craniofacial and tumor development.Four hundred and ninety-seven subjects born with oral clefts and 823 unaffected subjects were recruited. Twenty-nine markers in 13 genes were genotyped by the Taqman method. Chi-square was used to compare allele and genotype frequencies. Bonferroni correction for multiple testing was used and the established alpha was 0.0003. This study also used logistic regression to test if genetic variants were associated with oral clefts using positive family history of cancer and age as covariates.There was no association between family history of cancer and oral clefts (p = 0.51). None of the 1320 study participants had a diagnosis of cancer at the time of participation in the study. The marker rs4980700 in FGF3 was associated with oral clefts (p = 0.0002). Logistic regression analysis also provided evidence for gene-gene interaction between FGF3 (rs4980700) and PAX9 (rs2073242), increasing the risk for isolated oral clefts (p = 0.0003).FGF3 is associated with oral clefts and may interact with PAX9." @default.
- W2036616773 created "2016-06-24" @default.
- W2036616773 creator A5002718524 @default.
- W2036616773 creator A5004579331 @default.
- W2036616773 creator A5019557036 @default.
- W2036616773 creator A5023667688 @default.
- W2036616773 creator A5028650193 @default.
- W2036616773 creator A5029030960 @default.
- W2036616773 creator A5050720595 @default.
- W2036616773 creator A5052913876 @default.
- W2036616773 creator A5054541434 @default.
- W2036616773 creator A5065729214 @default.
- W2036616773 creator A5077950359 @default.
- W2036616773 creator A5087339643 @default.
- W2036616773 date "2014-04-04" @default.
- W2036616773 modified "2023-10-16" @default.
- W2036616773 title "Studies of genes involved in craniofacial development and tumorigenesis:<i>FGF3</i>contributes to isolated oral clefts and may interact with<i>PAX9</i>" @default.
- W2036616773 cites W1662926935 @default.
- W2036616773 cites W1855100791 @default.
- W2036616773 cites W1928400472 @default.
- W2036616773 cites W1961085741 @default.
- W2036616773 cites W1965222408 @default.
- W2036616773 cites W1965932514 @default.
- W2036616773 cites W1966682037 @default.
- W2036616773 cites W1982076953 @default.
- W2036616773 cites W1986819584 @default.
- W2036616773 cites W1987960325 @default.
- W2036616773 cites W1995038592 @default.
- W2036616773 cites W1999773307 @default.
- W2036616773 cites W2000042026 @default.
- W2036616773 cites W2012301024 @default.
- W2036616773 cites W2014739095 @default.
- W2036616773 cites W2032341434 @default.
- W2036616773 cites W2037705608 @default.
- W2036616773 cites W2039351120 @default.
- W2036616773 cites W2046786765 @default.
- W2036616773 cites W2060823106 @default.
- W2036616773 cites W2071628349 @default.
- W2036616773 cites W2072211572 @default.
- W2036616773 cites W2074344990 @default.
- W2036616773 cites W2082143738 @default.
- W2036616773 cites W2100535191 @default.
- W2036616773 cites W2111402916 @default.
- W2036616773 cites W2125750953 @default.
- W2036616773 cites W2129948470 @default.
- W2036616773 cites W2132578047 @default.
- W2036616773 cites W2132682597 @default.
- W2036616773 cites W2137691214 @default.
- W2036616773 cites W2140689100 @default.
- W2036616773 cites W2145108229 @default.
- W2036616773 cites W2154587258 @default.
- W2036616773 cites W2157116817 @default.
- W2036616773 cites W2158747582 @default.
- W2036616773 cites W2159552267 @default.
- W2036616773 cites W2170873634 @default.
- W2036616773 cites W2273874157 @default.
- W2036616773 cites W2334149595 @default.
- W2036616773 cites W4252627835 @default.
- W2036616773 doi "https://doi.org/10.3109/00016357.2014.903514" @default.
- W2036616773 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24697712" @default.
- W2036616773 hasPublicationYear "2014" @default.
- W2036616773 type Work @default.
- W2036616773 sameAs 2036616773 @default.
- W2036616773 citedByCount "9" @default.
- W2036616773 countsByYear W20366167732015 @default.
- W2036616773 countsByYear W20366167732017 @default.
- W2036616773 countsByYear W20366167732018 @default.
- W2036616773 countsByYear W20366167732019 @default.
- W2036616773 countsByYear W20366167732020 @default.
- W2036616773 countsByYear W20366167732021 @default.
- W2036616773 crossrefType "journal-article" @default.
- W2036616773 hasAuthorship W2036616773A5002718524 @default.
- W2036616773 hasAuthorship W2036616773A5004579331 @default.
- W2036616773 hasAuthorship W2036616773A5019557036 @default.
- W2036616773 hasAuthorship W2036616773A5023667688 @default.
- W2036616773 hasAuthorship W2036616773A5028650193 @default.
- W2036616773 hasAuthorship W2036616773A5029030960 @default.
- W2036616773 hasAuthorship W2036616773A5050720595 @default.
- W2036616773 hasAuthorship W2036616773A5052913876 @default.
- W2036616773 hasAuthorship W2036616773A5054541434 @default.
- W2036616773 hasAuthorship W2036616773A5065729214 @default.
- W2036616773 hasAuthorship W2036616773A5077950359 @default.
- W2036616773 hasAuthorship W2036616773A5087339643 @default.
- W2036616773 hasConcept C104317684 @default.
- W2036616773 hasConcept C105795698 @default.
- W2036616773 hasConcept C121608353 @default.
- W2036616773 hasConcept C126322002 @default.
- W2036616773 hasConcept C127808970 @default.
- W2036616773 hasConcept C135763542 @default.
- W2036616773 hasConcept C143998085 @default.
- W2036616773 hasConcept C151956035 @default.
- W2036616773 hasConcept C180754005 @default.
- W2036616773 hasConcept C2781179581 @default.
- W2036616773 hasConcept C2781245598 @default.
- W2036616773 hasConcept C33923547 @default.
- W2036616773 hasConcept C54355233 @default.
- W2036616773 hasConcept C555283112 @default.
- W2036616773 hasConcept C60644358 @default.