FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2036622010> ?p ?o ?g. }

• W2036622010 endingPage "1966" @default.
• W2036622010 startingPage "1958" @default.
• W2036622010 abstract "BACKGROUND The clinical significance of exercise-induced chest pain remains controversial, as reflected by sharply discordant clinical results within the medical literature. Thus, we developed a prospective study to compare the functional significance of silent versus symptomatic ischemia and to evaluate whether patient selection biases influence this analysis. METHODS AND RESULTS We evaluated 117 patients (mean age, 63 +/- 9 years) with ischemic ST-segment depression during treadmill testing. Each patient underwent Tl-201 myocardial perfusion single-photon emission computed tomography (SPECT) after exercise followed by 24-ambulatory ECG monitoring. Patients were divided into silent versus symptomatic cohorts and were compared for the degree of hemodynamic, exercise and ambulatory ECG, and thallium abnormalities during stress testing. Analyses were repeated as the patient population became increasingly restricted. Compared with the silent patients, patients with chest pain during exercise had a shorter exercise duration (P < .009), lower peak heart rate (P = .009) and double product (P = .005), lower heart rate threshold for ST depression (P < .05), more episodes of ambulatory ST-segment depression (P < .05), a higher frequency of ischemia abnormalities during Tl-201 SPECT (P = .02), and higher summed Tl reversibility scores (P = .002). As the population became increasingly restricted, the relative magnitude of differences in silent versus symptomatic cohorts diminished, whereas the absolute magnitude of ischemic abnormalities progressively increased in both cohorts. For example, within the restricted group having ischemia on both exercise and ambulatory ECG, 50% of the silent cohort had severe ischemia on Tl SPECT (five or more reversible defects) and more than one third demonstrated the ominous finding of transient left ventricular dilation after exercise. CONCLUSIONS The induction of chest pain is associated with substantially more functional abnormalities when it is analyzed in a relatively broad-spectrum coronary artery disease population; by contrast, chest pain tends to lose its apparent value as a clinical test parameter when its analysis is restricted to coronary artery disease populations with a greater a priori likelihood of manifesting inducible ischemia. These findings may help resolve some of the previous discordant literature reports." @default.
• W2036622010 created "2016-06-24" @default.
• W2036622010 creator A5013504140 @default.
• W2036622010 creator A5057121881 @default.
• W2036622010 creator A5062520509 @default.
• W2036622010 creator A5065807008 @default.
• W2036622010 date "1994-05-01" @default.
• W2036622010 modified "2023-10-18" @default.
• W2036622010 title "Is 'silent' myocardial ischemia really as severe as symptomatic ischemia? The analytical effect of patient selection biases." @default.
• W2036622010 cites W1967418580 @default.
• W2036622010 cites W1970262543 @default.
• W2036622010 cites W1970693618 @default.
• W2036622010 cites W1976151766 @default.
• W2036622010 cites W1978308484 @default.
• W2036622010 cites W1983876901 @default.
• W2036622010 cites W1986442893 @default.
• W2036622010 cites W1987521020 @default.
• W2036622010 cites W1992550861 @default.
• W2036622010 cites W1998170554 @default.
• W2036622010 cites W2001093698 @default.
• W2036622010 cites W2007111648 @default.
• W2036622010 cites W2007613238 @default.
• W2036622010 cites W2009478499 @default.
• W2036622010 cites W2011635920 @default.
• W2036622010 cites W2014050913 @default.
• W2036622010 cites W2016383344 @default.
• W2036622010 cites W2018502882 @default.
• W2036622010 cites W2023319637 @default.
• W2036622010 cites W2024590427 @default.
• W2036622010 cites W2028208595 @default.
• W2036622010 cites W2031624258 @default.
• W2036622010 cites W2035273375 @default.
• W2036622010 cites W2036565320 @default.
• W2036622010 cites W2037120995 @default.
• W2036622010 cites W2045326952 @default.
• W2036622010 cites W2045712219 @default.
• W2036622010 cites W2045758112 @default.
• W2036622010 cites W2080686773 @default.
• W2036622010 cites W2083183637 @default.
• W2036622010 cites W2088227329 @default.
• W2036622010 cites W2088724740 @default.
• W2036622010 cites W2090214030 @default.
• W2036622010 cites W2109148827 @default.
• W2036622010 cites W2121010227 @default.
• W2036622010 cites W2126298413 @default.
• W2036622010 cites W2132989961 @default.
• W2036622010 cites W2168371816 @default.
• W2036622010 cites W2334748255 @default.
• W2036622010 cites W2090296801 @default.
• W2036622010 doi "https://doi.org/10.1161/01.cir.89.5.1958" @default.
• W2036622010 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8181118" @default.
• W2036622010 hasPublicationYear "1994" @default.
• W2036622010 type Work @default.
• W2036622010 sameAs 2036622010 @default.
• W2036622010 citedByCount "62" @default.
• W2036622010 countsByYear W20366220102012 @default.
• W2036622010 countsByYear W20366220102013 @default.
• W2036622010 countsByYear W20366220102016 @default.
• W2036622010 countsByYear W20366220102020 @default.
• W2036622010 crossrefType "journal-article" @default.
• W2036622010 hasAuthorship W2036622010A5013504140 @default.
• W2036622010 hasAuthorship W2036622010A5057121881 @default.
• W2036622010 hasAuthorship W2036622010A5062520509 @default.
• W2036622010 hasAuthorship W2036622010A5065807008 @default.
• W2036622010 hasBestOaLocation W20366220101 @default.
• W2036622010 hasConcept C126322002 @default.
• W2036622010 hasConcept C139719470 @default.
• W2036622010 hasConcept C162324750 @default.
• W2036622010 hasConcept C164705383 @default.
• W2036622010 hasConcept C188816634 @default.
• W2036622010 hasConcept C2771771 @default.
• W2036622010 hasConcept C2776867660 @default.
• W2036622010 hasConcept C2777953023 @default.
• W2036622010 hasConcept C2778704086 @default.
• W2036622010 hasConcept C2780395512 @default.
• W2036622010 hasConcept C2908647359 @default.
• W2036622010 hasConcept C35785553 @default.
• W2036622010 hasConcept C500558357 @default.
• W2036622010 hasConcept C541997718 @default.
• W2036622010 hasConcept C71924100 @default.
• W2036622010 hasConcept C72563966 @default.
• W2036622010 hasConcept C84393581 @default.
• W2036622010 hasConcept C99454951 @default.
• W2036622010 hasConceptScore W2036622010C126322002 @default.
• W2036622010 hasConceptScore W2036622010C139719470 @default.
• W2036622010 hasConceptScore W2036622010C162324750 @default.
• W2036622010 hasConceptScore W2036622010C164705383 @default.
• W2036622010 hasConceptScore W2036622010C188816634 @default.
• W2036622010 hasConceptScore W2036622010C2771771 @default.
• W2036622010 hasConceptScore W2036622010C2776867660 @default.
• W2036622010 hasConceptScore W2036622010C2777953023 @default.
• W2036622010 hasConceptScore W2036622010C2778704086 @default.
• W2036622010 hasConceptScore W2036622010C2780395512 @default.
• W2036622010 hasConceptScore W2036622010C2908647359 @default.
• W2036622010 hasConceptScore W2036622010C35785553 @default.
• W2036622010 hasConceptScore W2036622010C500558357 @default.
• W2036622010 hasConceptScore W2036622010C541997718 @default.
• W2036622010 hasConceptScore W2036622010C71924100 @default.

• next