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• W2036635596 abstract "BackgroundVentriculostomy-associated infections are a serious complication of external ventricular drains. The objective of this study was to analyze the clinical features of and risk factors for such infections.MethodsWe retrospectively collected demographic and clinical data on patients with indwelling ventriculostomy catheters hospitalized in a teaching hospital from July 2001 to June 2006, comparing those with and without ventriculostomy-associated infections.ResultsA total of 197 drains (2910 catheter-days) placed in 155 patients were studied. Infections developed in 28 of the 197 (14.2%) drains. The duration from insertion to infection ranged from 7 to 36 days. The cut-off point of duration from insertion to infection was 15.5 days. Re-insertion because of catheter malfunction carried a high risk of infection (p < 0.001). Patients with infections had a longer intensive care unit stay (p = 0.001), longer duration of catheterization (p = 0.002), and a higher incidence of concurrent sepsis (p = 0.018), urinary tract infection (p = 0.011) and pneumonia (p = 0.004). Gram-negative bacilli were the leading pathogens (84%); Pseudomonas aeruginosa was the most common isolate. Polymicrobial infections occurred later than monomicrobial infections (p = 0.003).ConclusionsRepeated insertion and longer duration of drains are major risk factors for ventriculostomy-associated infections." @default.
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• W2036635596 date "2010-03-01" @default.
• W2036635596 modified "2023-09-29" @default.
• W2036635596 title "Infections associated with indwelling ventriculostomy catheters in a teaching hospital" @default.
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• W2036635596 doi "https://doi.org/10.1016/j.ijid.2009.04.006" @default.
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