FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2036640839> ?p ?o ?g. }

• W2036640839 abstract "The development of new therapeutic strategies for treatment of metastasized colorectal carcinoma requires biologically relevant and adequate animal models that generate both reproducible metastasis and the dissemination of tumor cells in the form of so-called minimal residual disease (MRD), an expression of the systemic character of neoplastic disease.We injected immunoincompetent nude mice intraportally with different numbers (1 x 10(5), 1 x 10(6) and 5 x 10(6) cells) of the human colon carcinoma cell lines HT-29 and SW-620 and investigated by histological studies and CK-20 RT-PCR the occurrence of hematogenous metastases and the dissemination of human tumor cells in bone marrow.Only the injection of 1 x 10(6) cells of each colon carcinoma cell line produced acceptable perioperative mortality with reproducible induction of hepatic metastases in up to 89% of all animals. The injection of 1 x 10(6) cells also generated tumor cell dissemination in the bone marrow in up to 63% of animals with hepatic metastases.The present intraportal injection model in immunoincompetent nude mice represents a biologically relevant and adequate animal model for the induction of both reproducible hepatic metastasis and tumor cell dissemination in the bone marrow as a sign of MRD." @default.
• W2036640839 created "2016-06-24" @default.
• W2036640839 creator A5006396543 @default.
• W2036640839 creator A5009234233 @default.
• W2036640839 creator A5016167769 @default.
• W2036640839 creator A5024266144 @default.
• W2036640839 creator A5029444162 @default.
• W2036640839 creator A5045379119 @default.
• W2036640839 creator A5046610786 @default.
• W2036640839 creator A5047474277 @default.
• W2036640839 creator A5058734088 @default.
• W2036640839 creator A5073266858 @default.
• W2036640839 date "2009-01-24" @default.
• W2036640839 modified "2023-09-26" @default.
• W2036640839 title "The intraportal injection model: A practical animal model for hepatic metastases and tumor cell dissemination in human colon cancer" @default.
• W2036640839 cites W1518520618 @default.
• W2036640839 cites W1890097486 @default.
• W2036640839 cites W1963592300 @default.
• W2036640839 cites W1972529863 @default.
• W2036640839 cites W1989743176 @default.
• W2036640839 cites W2004480635 @default.
• W2036640839 cites W2024041816 @default.
• W2036640839 cites W2032837380 @default.
• W2036640839 cites W2047504893 @default.
• W2036640839 cites W2056874077 @default.
• W2036640839 cites W2080275318 @default.
• W2036640839 cites W2082539454 @default.
• W2036640839 cites W2085739446 @default.
• W2036640839 cites W2087617745 @default.
• W2036640839 cites W2090309282 @default.
• W2036640839 cites W2093114824 @default.
• W2036640839 cites W2108296770 @default.
• W2036640839 cites W2128692771 @default.
• W2036640839 cites W2142564546 @default.
• W2036640839 cites W2157769714 @default.
• W2036640839 doi "https://doi.org/10.1186/1471-2407-9-29" @default.
• W2036640839 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2648996" @default.
• W2036640839 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19166621" @default.
• W2036640839 hasPublicationYear "2009" @default.
• W2036640839 type Work @default.
• W2036640839 sameAs 2036640839 @default.
• W2036640839 citedByCount "23" @default.
• W2036640839 countsByYear W20366408392013 @default.
• W2036640839 countsByYear W20366408392014 @default.
• W2036640839 countsByYear W20366408392015 @default.
• W2036640839 countsByYear W20366408392016 @default.
• W2036640839 countsByYear W20366408392017 @default.
• W2036640839 countsByYear W20366408392019 @default.
• W2036640839 countsByYear W20366408392020 @default.
• W2036640839 countsByYear W20366408392021 @default.
• W2036640839 crossrefType "journal-article" @default.
• W2036640839 hasAuthorship W2036640839A5006396543 @default.
• W2036640839 hasAuthorship W2036640839A5009234233 @default.
• W2036640839 hasAuthorship W2036640839A5016167769 @default.
• W2036640839 hasAuthorship W2036640839A5024266144 @default.
• W2036640839 hasAuthorship W2036640839A5029444162 @default.
• W2036640839 hasAuthorship W2036640839A5045379119 @default.
• W2036640839 hasAuthorship W2036640839A5046610786 @default.
• W2036640839 hasAuthorship W2036640839A5047474277 @default.
• W2036640839 hasAuthorship W2036640839A5058734088 @default.
• W2036640839 hasAuthorship W2036640839A5073266858 @default.
• W2036640839 hasBestOaLocation W20366408391 @default.
• W2036640839 hasConcept C121608353 @default.
• W2036640839 hasConcept C126322002 @default.
• W2036640839 hasConcept C142724271 @default.
• W2036640839 hasConcept C143998085 @default.
• W2036640839 hasConcept C2779013556 @default.
• W2036640839 hasConcept C2779823535 @default.
• W2036640839 hasConcept C2780007613 @default.
• W2036640839 hasConcept C2780140570 @default.
• W2036640839 hasConcept C2780283643 @default.
• W2036640839 hasConcept C502942594 @default.
• W2036640839 hasConcept C526805850 @default.
• W2036640839 hasConcept C54355233 @default.
• W2036640839 hasConcept C71924100 @default.
• W2036640839 hasConcept C81885089 @default.
• W2036640839 hasConcept C86803240 @default.
• W2036640839 hasConceptScore W2036640839C121608353 @default.
• W2036640839 hasConceptScore W2036640839C126322002 @default.
• W2036640839 hasConceptScore W2036640839C142724271 @default.
• W2036640839 hasConceptScore W2036640839C143998085 @default.
• W2036640839 hasConceptScore W2036640839C2779013556 @default.
• W2036640839 hasConceptScore W2036640839C2779823535 @default.
• W2036640839 hasConceptScore W2036640839C2780007613 @default.
• W2036640839 hasConceptScore W2036640839C2780140570 @default.
• W2036640839 hasConceptScore W2036640839C2780283643 @default.
• W2036640839 hasConceptScore W2036640839C502942594 @default.
• W2036640839 hasConceptScore W2036640839C526805850 @default.
• W2036640839 hasConceptScore W2036640839C54355233 @default.
• W2036640839 hasConceptScore W2036640839C71924100 @default.
• W2036640839 hasConceptScore W2036640839C81885089 @default.
• W2036640839 hasConceptScore W2036640839C86803240 @default.
• W2036640839 hasIssue "1" @default.
• W2036640839 hasLocation W20366408391 @default.
• W2036640839 hasLocation W20366408392 @default.
• W2036640839 hasLocation W20366408393 @default.
• W2036640839 hasLocation W20366408394 @default.
• W2036640839 hasLocation W20366408395 @default.
• W2036640839 hasOpenAccess W2036640839 @default.
• W2036640839 hasPrimaryLocation W20366408391 @default.

• next