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• W2036661829 abstract "We describe the synthesis, properties, and application of a new fluorescent potassium chemosensor, KS2, for K(+) sensing and imaging in live cells. By virtue of a strong electron-withdrawing group, 2-dicyanomethylene-3-cyano-4,5,5-trimethyl-2,5-dihydrofuran (TCF), with a triazacryptand ligand, the new sensor can respond to K(+) up to 1.6 M. This is the first highly selective intracellular sensor suitable for sensing K(+) over a broad and high concentration range. Confocal fluorescence microscopy has established the utility of KS2 for live-cell K(+) detection. The application of KS2 combined with other sensors will be of great benefit for investigating cellular metabolism, detecting and diagnosing diseases including cancer, and monitoring responses to therapy." @default.
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• W2036661829 date "2011-10-27" @default.
• W2036661829 modified "2023-10-16" @default.
• W2036661829 title "A New Highly Selective Fluorescent K⁺ Sensor" @default.
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• W2036661829 doi "https://doi.org/10.1021/ja207345s" @default.
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