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- W2036670046 abstract "The partial characterization of a bacteriocin produced by a human Lactobacillus delbrueckii isolate with probiotic potential.A bacterocin, UO004, was partially purified by cation exchange followed by a hydrophobic interaction column, biochemically characterized and the N-terminal region sequenced. Bacteriocin UO004 was found to be a hydrophobic, heat-stable polypeptide with an apparent molecular mass of 6 kDa. It was also stable and active over a wide pH range.The active compound was proteinaceous, heat-stable, and had a bactericidal (and bacteriolytic) mode of action on a limited number of micro-organisms. Such a narrow spectrum of activity is typical for bacteriocins produced by intestinal Lactobacillus.Bacteriocin UO004 from a probiotic strain is a new compound that does not share any homology with any other known lactic acid bacteria bacteriocin. Furthermore, Lact. delbrueckii is regarded as a suitable starter for the production of fermented milks." @default.
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- W2036670046 date "2001-08-02" @default.
- W2036670046 modified "2023-09-27" @default.
- W2036670046 title "Partial characterization of a bacteriocin produced by Lactobacillus delbrueckii subsp. lactis UO004, an intestinal isolate with probiotic potential" @default.
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- W2036670046 doi "https://doi.org/10.1046/j.1365-2672.2001.01403.x" @default.
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