Matches in SemOpenAlex for { <https://semopenalex.org/work/W2036671167> ?p ?o ?g. }
Showing items 1 to 80 of
80
with 100 items per page.
- W2036671167 endingPage "1350" @default.
- W2036671167 startingPage "1347" @default.
- W2036671167 abstract "Inhibition of a β-lactamase of Streptomyces cacaoi by CP-45, 899, izumenolide and cephamycins was investigated and compared with that of a β-lactamase of Bacillus cereus. S. cacaoi enzyme could not hydrolyze CP-45, 899. Instead, hydrolysis of benzylpenicillin by the enzyme was inhibited in the presence of CP-45, 899. Although inhibition increased gradually with time, the inhibition line produced by CP-45, 899 with time was less curved than that produced by clavulanic acid and PS-5. Furthermore, preincubation of S. cacaoi β-lactamase with CP-45, 899 for up to 120 seconds did not obviously affect the degree of inhibition. When the concentration was lowered, it behaved as a competitive inhibitor, a Ki value being 6.2×10-7 M. Izumenolide, on the other hand, did not inhibit the enzyme activity of S. cacaoi β-lactamase at 1.28×10-4M, although it inhibited B. cereus enzyme slightly in a competitive manner. Oganomycins were inert to the both β-lactamases." @default.
- W2036671167 created "2016-06-24" @default.
- W2036671167 creator A5012078855 @default.
- W2036671167 creator A5064331837 @default.
- W2036671167 date "1981-01-01" @default.
- W2036671167 modified "2023-10-18" @default.
- W2036671167 title "Interaction of .BETA.-lactamase of Streptomyces cacaoi. II. Cp-45,899, Izumenolide and cephamycins." @default.
- W2036671167 cites W1534070776 @default.
- W2036671167 cites W1964191427 @default.
- W2036671167 cites W1980884715 @default.
- W2036671167 cites W2037223904 @default.
- W2036671167 cites W2051620446 @default.
- W2036671167 cites W2060907003 @default.
- W2036671167 cites W2079375100 @default.
- W2036671167 doi "https://doi.org/10.7164/antibiotics.34.1347" @default.
- W2036671167 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6273376" @default.
- W2036671167 hasPublicationYear "1981" @default.
- W2036671167 type Work @default.
- W2036671167 sameAs 2036671167 @default.
- W2036671167 citedByCount "1" @default.
- W2036671167 crossrefType "journal-article" @default.
- W2036671167 hasAuthorship W2036671167A5012078855 @default.
- W2036671167 hasAuthorship W2036671167A5064331837 @default.
- W2036671167 hasBestOaLocation W20366711671 @default.
- W2036671167 hasConcept C174802600 @default.
- W2036671167 hasConcept C181199279 @default.
- W2036671167 hasConcept C185592680 @default.
- W2036671167 hasConcept C2776060363 @default.
- W2036671167 hasConcept C2776341680 @default.
- W2036671167 hasConcept C2777118263 @default.
- W2036671167 hasConcept C2777915650 @default.
- W2036671167 hasConcept C2779920670 @default.
- W2036671167 hasConcept C2780201653 @default.
- W2036671167 hasConcept C2780373777 @default.
- W2036671167 hasConcept C501593827 @default.
- W2036671167 hasConcept C523546767 @default.
- W2036671167 hasConcept C54355233 @default.
- W2036671167 hasConcept C55493867 @default.
- W2036671167 hasConcept C86803240 @default.
- W2036671167 hasConcept C89423630 @default.
- W2036671167 hasConcept C94412978 @default.
- W2036671167 hasConceptScore W2036671167C174802600 @default.
- W2036671167 hasConceptScore W2036671167C181199279 @default.
- W2036671167 hasConceptScore W2036671167C185592680 @default.
- W2036671167 hasConceptScore W2036671167C2776060363 @default.
- W2036671167 hasConceptScore W2036671167C2776341680 @default.
- W2036671167 hasConceptScore W2036671167C2777118263 @default.
- W2036671167 hasConceptScore W2036671167C2777915650 @default.
- W2036671167 hasConceptScore W2036671167C2779920670 @default.
- W2036671167 hasConceptScore W2036671167C2780201653 @default.
- W2036671167 hasConceptScore W2036671167C2780373777 @default.
- W2036671167 hasConceptScore W2036671167C501593827 @default.
- W2036671167 hasConceptScore W2036671167C523546767 @default.
- W2036671167 hasConceptScore W2036671167C54355233 @default.
- W2036671167 hasConceptScore W2036671167C55493867 @default.
- W2036671167 hasConceptScore W2036671167C86803240 @default.
- W2036671167 hasConceptScore W2036671167C89423630 @default.
- W2036671167 hasConceptScore W2036671167C94412978 @default.
- W2036671167 hasIssue "10" @default.
- W2036671167 hasLocation W20366711671 @default.
- W2036671167 hasLocation W20366711672 @default.
- W2036671167 hasOpenAccess W2036671167 @default.
- W2036671167 hasPrimaryLocation W20366711671 @default.
- W2036671167 hasRelatedWork W1982471582 @default.
- W2036671167 hasRelatedWork W2028886030 @default.
- W2036671167 hasRelatedWork W2033841549 @default.
- W2036671167 hasRelatedWork W2034507089 @default.
- W2036671167 hasRelatedWork W2044902903 @default.
- W2036671167 hasRelatedWork W2065838317 @default.
- W2036671167 hasRelatedWork W2124581769 @default.
- W2036671167 hasRelatedWork W2131950501 @default.
- W2036671167 hasRelatedWork W2247246598 @default.
- W2036671167 hasRelatedWork W3035186302 @default.
- W2036671167 hasVolume "34" @default.
- W2036671167 isParatext "false" @default.
- W2036671167 isRetracted "false" @default.
- W2036671167 magId "2036671167" @default.
- W2036671167 workType "article" @default.