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• W2036680765 abstract "Pb2+ is a very effective catalyst for the template-directed self-condensation of guanosine 5′-phosphorimidazolide on a polycytidylate template. In the presence of 0.01 m-Pb2+ at 0 °C, up to 85% of the input ImpG † is converted to a mixture of oligomers with a mean chain length of up to 17. Substantial amounts of material longer than (pG)40 are formed. About half the ImpG reacts within an hour. The oligomeric products are predominantly (2′–5′)-linked. If poly(C) is incubated with ImpG and an equimolar quantity of the corresponding derivative of adenosine, uridine or cytidine, the “incorrect” nucleotide, is incorporated about 10% as often as G." @default.
• W2036680765 created "2016-06-24" @default.
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• W2036680765 date "1980-10-01" @default.
• W2036680765 modified "2023-10-16" @default.
• W2036680765 title "Efficient catalysis of polycytidylic acid-directed oligoguanylate formation by Pb2+" @default.
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• W2036680765 doi "https://doi.org/10.1016/0022-2836(80)90263-6" @default.
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