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- W2036692322 abstract "A 2-response operant taste discrimination procedure, modified to assess taste sensitivity in water-restricted C57BL/6J mice, revealed a detection threshold of 0.065 M sodium chloride. Amiloride increased the threshold by approximately 1 log10 unit. These results are the first to demonstrate the necessity of the amiloride-sensitive taste transduction pathway in the normal detection of low concentrations of sodium chloride in mice and provide a functional context in which to evaluate electrophysiological findings. Two-bottle preference tests performed with these mice and additional naive mice revealed only marginal, if any, effects of amiloride on salt intake behavior, highlighting the importance of considering the relative attributes and limitations of different behavioral assays of taste function." @default.
- W2036692322 created "2016-06-24" @default.
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- W2036692322 date "2002-01-01" @default.
- W2036692322 modified "2023-09-23" @default.
- W2036692322 title "The effect of amiloride on operantly conditioned performance in an NaCl taste detection task and NaCl preference in C57BL/6J mice." @default.
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- W2036692322 doi "https://doi.org/10.1037//0735-7044.116.1.149" @default.
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