FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2036693083> ?p ?o ?g. }

• W2036693083 abstract "Local cooling of the testis was reported to cause testicular abnormality, but there is no information regarding the effect of whole body cooling, such as hypothermia on spermatogenesis. We investigated whether hypothermia would cause testicular toxicity in mice. Male mice were administered with a single intraperitoneal dose of 100mg/kg of reserpine. The rectal temperature decreased to 29 degrees C 6h post dosing and thereafter sustained at lower values (24-25 degrees C) until 96 h post dosing. The histopathological examination of the testis showed nuclear vacuolation of round spermatids at stages I-V in mice examined 24, 48, 72 and 96 h post dosing. The lesions were more severe in the groups examined 72 and 96 h post dosing than in the groups examined 24 and 48 h post dosing. These results suggested that hypothermia condition at lower than 30 degrees C and sustained for more than 18 h could induce nuclear vacuolation of round spermatids at stages I-V in the testis. In order to demonstrate that the testicular lesion in the reserpine-treated mice was induced by hypothermia, mice were given a single intraperitoneal dose of 100mg/kg of reserpine, and each dosed group was housed under different environmental conditions for 72 h; one consisted of housing the mice individually at room temperature, and the other consisted of housing the mice individually under heated condition. In the mice administered with reserpine and housed at room temperature, hypothermia below 30 degrees C with a minimal of 26 degrees C was observed for 66 h. In contrast, the mice administered with reserpine and housed under heated condition maintained the rectal temperature of 33-36 degrees C. Nuclear vacuolation of round spermatids at stages I-V in the testis was observed in reserpine-treated mice maintained at room temperature, but not in reserpine-treated mice kept under heated condition. These data strongly indicated that nuclear vacuolation of round spermatids at stages I-V observed in reserpine-treated mice was related to hypothermia." @default.
• W2036693083 created "2016-06-24" @default.
• W2036693083 creator A5005177820 @default.
• W2036693083 creator A5012348681 @default.
• W2036693083 creator A5026724215 @default.
• W2036693083 creator A5052468635 @default.
• W2036693083 creator A5069360562 @default.
• W2036693083 date "2007-11-01" @default.
• W2036693083 modified "2023-09-24" @default.
• W2036693083 title "Hypothermia-related testicular toxicity of reserpine in mice" @default.
• W2036693083 cites W1498186062 @default.
• W2036693083 cites W1966275061 @default.
• W2036693083 cites W1978373639 @default.
• W2036693083 cites W2003579489 @default.
• W2036693083 cites W2009934685 @default.
• W2036693083 cites W2028830121 @default.
• W2036693083 cites W2042673348 @default.
• W2036693083 cites W2045999154 @default.
• W2036693083 cites W2055988619 @default.
• W2036693083 cites W2067561118 @default.
• W2036693083 cites W2068045830 @default.
• W2036693083 cites W2096027168 @default.
• W2036693083 cites W2159792243 @default.
• W2036693083 cites W2345932926 @default.
• W2036693083 cites W4251408749 @default.
• W2036693083 doi "https://doi.org/10.1016/j.etp.2007.05.006" @default.
• W2036693083 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17892928" @default.
• W2036693083 hasPublicationYear "2007" @default.
• W2036693083 type Work @default.
• W2036693083 sameAs 2036693083 @default.
• W2036693083 citedByCount "8" @default.
• W2036693083 countsByYear W20366930832012 @default.
• W2036693083 countsByYear W20366930832014 @default.
• W2036693083 countsByYear W20366930832015 @default.
• W2036693083 countsByYear W20366930832016 @default.
• W2036693083 countsByYear W20366930832017 @default.
• W2036693083 crossrefType "journal-article" @default.
• W2036693083 hasAuthorship W2036693083A5005177820 @default.
• W2036693083 hasAuthorship W2036693083A5012348681 @default.
• W2036693083 hasAuthorship W2036693083A5026724215 @default.
• W2036693083 hasAuthorship W2036693083A5052468635 @default.
• W2036693083 hasAuthorship W2036693083A5069360562 @default.
• W2036693083 hasConcept C123765429 @default.
• W2036693083 hasConcept C126322002 @default.
• W2036693083 hasConcept C134018914 @default.
• W2036693083 hasConcept C142724271 @default.
• W2036693083 hasConcept C2777288759 @default.
• W2036693083 hasConcept C2777390192 @default.
• W2036693083 hasConcept C2777842393 @default.
• W2036693083 hasConcept C2781156865 @default.
• W2036693083 hasConcept C29730261 @default.
• W2036693083 hasConcept C71924100 @default.
• W2036693083 hasConceptScore W2036693083C123765429 @default.
• W2036693083 hasConceptScore W2036693083C126322002 @default.
• W2036693083 hasConceptScore W2036693083C134018914 @default.
• W2036693083 hasConceptScore W2036693083C142724271 @default.
• W2036693083 hasConceptScore W2036693083C2777288759 @default.
• W2036693083 hasConceptScore W2036693083C2777390192 @default.
• W2036693083 hasConceptScore W2036693083C2777842393 @default.
• W2036693083 hasConceptScore W2036693083C2781156865 @default.
• W2036693083 hasConceptScore W2036693083C29730261 @default.
• W2036693083 hasConceptScore W2036693083C71924100 @default.
• W2036693083 hasLocation W20366930831 @default.
• W2036693083 hasLocation W20366930832 @default.
• W2036693083 hasOpenAccess W2036693083 @default.
• W2036693083 hasPrimaryLocation W20366930831 @default.
• W2036693083 hasRelatedWork W1984541950 @default.
• W2036693083 hasRelatedWork W2011792914 @default.
• W2036693083 hasRelatedWork W2017700029 @default.
• W2036693083 hasRelatedWork W2026307684 @default.
• W2036693083 hasRelatedWork W2032619651 @default.
• W2036693083 hasRelatedWork W2052905250 @default.
• W2036693083 hasRelatedWork W2065996907 @default.
• W2036693083 hasRelatedWork W2072738462 @default.
• W2036693083 hasRelatedWork W2094392260 @default.
• W2036693083 hasRelatedWork W2130660566 @default.
• W2036693083 isParatext "false" @default.
• W2036693083 isRetracted "false" @default.
• W2036693083 magId "2036693083" @default.
• W2036693083 workType "article" @default.