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• W2036694872 abstract "You have accessJournal of UrologyKidney Cancer: Evaluation and Staging I1 Apr 2012580 RADIOLOGICAL PREDICTION OF PRESERVED RENAL MASS IN PATIENTS UNDERGOING LAPAROSCOPIC PARTIAL NEPHRECTOMY CORRELATION WITH OPERATIVE AND FUNCTIONAL OUTCOMES Scott Leslie, Syed Rahmanuddin, Eric Yi-Hsiu Huang, Dennis J. Lee, Andre Luis de Castro Abreu, Alvin Goh, Andre K. Berger, Jie Cai, Monish Aron, Mihir M. Desai, Vinay A. Duddalwar, and Inderbir S. Gill Scott LeslieScott Leslie Los Angeles, CA More articles by this author , Syed RahmanuddinSyed Rahmanuddin Los Angeles, CA More articles by this author , Eric Yi-Hsiu HuangEric Yi-Hsiu Huang Los Angeles, CA More articles by this author , Dennis J. LeeDennis J. Lee Los Angeles, CA More articles by this author , Andre Luis de Castro AbreuAndre Luis de Castro Abreu Los Angeles, CA More articles by this author , Alvin GohAlvin Goh Los Angeles, CA More articles by this author , Andre K. BergerAndre K. Berger Los Angeles, CA More articles by this author , Jie CaiJie Cai Los Angeles, CA More articles by this author , Monish AronMonish Aron Los Angeles, CA More articles by this author , Mihir M. DesaiMihir M. Desai Los Angeles, CA More articles by this author , Vinay A. DuddalwarVinay A. Duddalwar Los Angeles, CA More articles by this author , and Inderbir S. GillInderbir S. Gill Los Angeles, CA More articles by this author View All Author Informationhttps://doi.org/10.1016/j.juro.2012.02.656AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookTwitterLinked InEmail INTRODUCTION AND OBJECTIVES Preserved renal mass following partial nephrectomy (PN) correlates with postoperative renal function. We assessed the accuracy of preoperative radiological prediction of preserved renal mass using a novel CT image-rendering program (3D Synapse - Fuji film©). Correlation is made with the volume of the resected specimen and post-operative renal function. METHODS We identified 100 patients undergoing laparoscopic partial nephrectomy (LPN) for a solitary renal mass. The preoperative CT scan was assessed using advanced image-processing software to measure the volume of both kidneys, the tumor volume and to calculate the predicted volume of preserved renal mass by subtracting the predicted resection volume. The predicted resection volume included the tumor as well as a surgical margin of normal renal parenchyma (see image). The actual resected volume was calculated by measuring the volume of the specimen on the back table following excision. Predicted postoperative eGFR was calculated by multiplying the preoperative eGFR with the predicted functional remaining volume (FRV). Predicted postop eGFR = Preop eGFR × % FRV RESULTS All patients successfully underwent zero-ischemia LPN, with or without robotic assistance. Mean age was 60.5 years. The mean tumor volume was 21.3 ml, mean predicted resected volume (tumor volume + predicted resection margin) was 45.7 ml and mean predicted FRV was 92.5%. Comparing the predicted resected volume with the actual resected volume demonstrated excellent correlation, with a Spearman Correlation Coefficient of r=0.91 (p<0.0001). The mean preop eGFR was 80.4 ml/min. The mean predicted postop eGFR was calculated using the above formula and was found to be 74.6 ml/min. There was excellent correlation between predicted postop eGFR and the actual postop eGFR, r=0.93 (p<0.0001). Reproducibility between surgeons was excellent with an interobserver correlation of r=0.98 (p<0.0001) for predicted resection volumes. CONCLUSIONS We describe a novel technique of pre-operatively predicting the surgically resected volume and the predicted post-operative eGFR. Good correlation with the actual resected specimen and the actual post-operative eGFR is seen. Advanced image-processing software demonstrates excellent applicability for pre-operative surgical planning for complex procedures such as PN. The volume calculations allow the prediction of functional outcomes, which hold prognostic significance for patients with already impaired renal function. © 2012 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 187Issue 4SApril 2012Page: e236-e237 Advertisement Copyright & Permissions© 2012 by American Urological Association Education and Research, Inc.MetricsAuthor Information Scott Leslie Los Angeles, CA More articles by this author Syed Rahmanuddin Los Angeles, CA More articles by this author Eric Yi-Hsiu Huang Los Angeles, CA More articles by this author Dennis J. Lee Los Angeles, CA More articles by this author Andre Luis de Castro Abreu Los Angeles, CA More articles by this author Alvin Goh Los Angeles, CA More articles by this author Andre K. Berger Los Angeles, CA More articles by this author Jie Cai Los Angeles, CA More articles by this author Monish Aron Los Angeles, CA More articles by this author Mihir M. Desai Los Angeles, CA More articles by this author Vinay A. Duddalwar Los Angeles, CA More articles by this author Inderbir S. Gill Los Angeles, CA More articles by this author Expand All Advertisement Advertisement PDF downloadLoading ..." @default.
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• W2036694872 title "580 RADIOLOGICAL PREDICTION OF PRESERVED RENAL MASS IN PATIENTS UNDERGOING LAPAROSCOPIC PARTIAL NEPHRECTOMY CORRELATION WITH OPERATIVE AND FUNCTIONAL OUTCOMES" @default.
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