FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2036697846> ?p ?o ?g. }

• W2036697846 endingPage "S9" @default.
• W2036697846 startingPage "S2" @default.
• W2036697846 abstract "Several factors may contribute to the propensity for the developing brain to have seizures and develop epilepsy. Hypersynchrony of neuronal circuits contributes to the seizure potential and several neurobiological features of the immature brain may support synchronized neuronal firing. The immature cerebral cortex and hippocampus have an increased density of synapses compared to adults and also a higher density of gap junctions and of excitatory amino acid receptors. Enhanced regenerative responses to injury in the developing brain may also contribute to the formation of abnormal hippocampal connections that support epilepsy. Molecular mechanisms that contribute to enhanced synaptic plasticity in the child's brain can also contribute to epileptogenesis in certain circumstances. The phenomenon of kindling, where repeated electrical stimulation of neuronal circuits leads to the development of epileptic seizures, is easily elicited in young animals. Long-term potentiation (LTP), where repeated synaptic stimulation leads to a reduced threshold for activation of that pathway and enhanced postsynaptic potentials, is much more robust in the immature cerebral cortex and may contribute to kindling and epileptogenesis. Age related enhancement of N-methyl-D-aspartate-type glutamate receptors, which are important for the activity dependent plasticity in the developing brain, appears to participate in LTP. This information suggests that normal developmental features of synaptic development make the immature brain more excitable than the adult brain and may contribute to epileptogenesis." @default.
• W2036697846 created "2016-06-24" @default.
• W2036697846 creator A5048940403 @default.
• W2036697846 date "1996-02-01" @default.
• W2036697846 modified "2023-10-17" @default.
• W2036697846 title "Developmental Aspects of Epileptogenesis" @default.
• W2036697846 cites W1522767593 @default.
• W2036697846 cites W1627298799 @default.
• W2036697846 cites W1827373965 @default.
• W2036697846 cites W1860455432 @default.
• W2036697846 cites W1893829779 @default.
• W2036697846 cites W1965842622 @default.
• W2036697846 cites W1970958687 @default.
• W2036697846 cites W1971869900 @default.
• W2036697846 cites W1971931358 @default.
• W2036697846 cites W1975697777 @default.
• W2036697846 cites W1977887400 @default.
• W2036697846 cites W1982043728 @default.
• W2036697846 cites W1985333845 @default.
• W2036697846 cites W1986794921 @default.
• W2036697846 cites W1989685432 @default.
• W2036697846 cites W1992731142 @default.
• W2036697846 cites W1997567157 @default.
• W2036697846 cites W2003802096 @default.
• W2036697846 cites W2009782005 @default.
• W2036697846 cites W2013902161 @default.
• W2036697846 cites W2014997471 @default.
• W2036697846 cites W2015747929 @default.
• W2036697846 cites W2017213222 @default.
• W2036697846 cites W2018197873 @default.
• W2036697846 cites W2024945446 @default.
• W2036697846 cites W2034377493 @default.
• W2036697846 cites W2038465691 @default.
• W2036697846 cites W2041024256 @default.
• W2036697846 cites W2041525670 @default.
• W2036697846 cites W2044472211 @default.
• W2036697846 cites W2047859888 @default.
• W2036697846 cites W2051493425 @default.
• W2036697846 cites W2053007646 @default.
• W2036697846 cites W2057724184 @default.
• W2036697846 cites W2058107876 @default.
• W2036697846 cites W2061148748 @default.
• W2036697846 cites W2061658975 @default.
• W2036697846 cites W2063670877 @default.
• W2036697846 cites W2065169750 @default.
• W2036697846 cites W2066162854 @default.
• W2036697846 cites W206744106 @default.
• W2036697846 cites W2071789460 @default.
• W2036697846 cites W2073421321 @default.
• W2036697846 cites W2077369265 @default.
• W2036697846 cites W2080501570 @default.
• W2036697846 cites W2083046441 @default.
• W2036697846 cites W2083329760 @default.
• W2036697846 cites W2084169044 @default.
• W2036697846 cites W2094099092 @default.
• W2036697846 cites W2104766969 @default.
• W2036697846 cites W2151700529 @default.
• W2036697846 cites W2160789742 @default.
• W2036697846 cites W2160987264 @default.
• W2036697846 cites W77091309 @default.
• W2036697846 doi "https://doi.org/10.1111/j.1528-1157.1996.tb06018.x" @default.
• W2036697846 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8647048" @default.
• W2036697846 hasPublicationYear "1996" @default.
• W2036697846 type Work @default.
• W2036697846 sameAs 2036697846 @default.
• W2036697846 citedByCount "61" @default.
• W2036697846 countsByYear W20366978462012 @default.
• W2036697846 countsByYear W20366978462015 @default.
• W2036697846 countsByYear W20366978462017 @default.
• W2036697846 countsByYear W20366978462018 @default.
• W2036697846 countsByYear W20366978462023 @default.
• W2036697846 crossrefType "journal-article" @default.
• W2036697846 hasAuthorship W2036697846A5048940403 @default.
• W2036697846 hasConcept C100691959 @default.
• W2036697846 hasConcept C112592302 @default.
• W2036697846 hasConcept C148762608 @default.
• W2036697846 hasConcept C15744967 @default.
• W2036697846 hasConcept C169760540 @default.
• W2036697846 hasConcept C170493617 @default.
• W2036697846 hasConcept C17077164 @default.
• W2036697846 hasConcept C24998067 @default.
• W2036697846 hasConcept C25274449 @default.
• W2036697846 hasConcept C2778186239 @default.
• W2036697846 hasConcept C2778302826 @default.
• W2036697846 hasConcept C2781161787 @default.
• W2036697846 hasConcept C47611674 @default.
• W2036697846 hasConcept C55493867 @default.
• W2036697846 hasConcept C57236427 @default.
• W2036697846 hasConcept C61174792 @default.
• W2036697846 hasConcept C86803240 @default.
• W2036697846 hasConcept C98229152 @default.
• W2036697846 hasConceptScore W2036697846C100691959 @default.
• W2036697846 hasConceptScore W2036697846C112592302 @default.
• W2036697846 hasConceptScore W2036697846C148762608 @default.
• W2036697846 hasConceptScore W2036697846C15744967 @default.
• W2036697846 hasConceptScore W2036697846C169760540 @default.
• W2036697846 hasConceptScore W2036697846C170493617 @default.
• W2036697846 hasConceptScore W2036697846C17077164 @default.

• next