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- W2036697895 abstract "Glutathione S-transferase A form (GST-A) is increased markedly in rat preneoplastic hepatic lesions such as hyperplastic nodules induced by diethylnitrosamine followed by administration of N-2-fluorenylacetamide. GST-A was also significantly increased in livers of rats after short-term administration of some drugs. The increased activity and protein content of GST-A were demonstrated by CM-Sephadex C-50 column chromatography as well as by two-dimensional polyacrylamide gel electrophoresis following immuno-affinity column chromatography using antibody against GST-A. Immunologically, GST-A crossreacted strongly with GST-C, weakly with GST-C2, but not with ligandin, GST-B, or GST-AA. It was confirmed by subunit recombination that GST-C is a heterodimer composed of the subunits of homodimers, GST-A and GST-C2." @default.
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- W2036697895 date "1983-04-01" @default.
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- W2036697895 title "Properties of the increased glutathione S-transferase a form in rat preneoplastic hepatic lesions induced by chemical carcinogens" @default.
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- W2036697895 doi "https://doi.org/10.1016/0006-291x(83)91791-6" @default.
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