Matches in SemOpenAlex for { <https://semopenalex.org/work/W2036698942> ?p ?o ?g. }
- W2036698942 endingPage "946" @default.
- W2036698942 startingPage "938" @default.
- W2036698942 abstract "Abstract Phosphoinositides are important molecules that serve as second messengers and bind to a complex array of proteins modulating their subcellular location and activity. The enzymes that metabolize phosphoinositides can in some cases serve to terminate the signaling actions of phosphoinositides. The inositol polyphosphate 5-phosphatases (5PTases) comprise a large protein family that hydrolyzes 5-phosphates from a variety of inositol phosphate and phosphoinositide substrates. We previously reported the identification of 15 putative 5PTase genes in Arabidopsis and have shown that overexpression of the At5PTase1 gene can alter abscisic acid signaling. At5PTase1 and At5PTase2 have been shown to hydrolyze the 5-phosphate from inositol phosphate substrates. We have examined the substrate specificity of the At5PTase11 protein, which is one of the smallest predicted 5PTases found in any organism. We report here that the At5PTase11 gene encodes an active 5PTase enzyme that can only dephosphorylate phosphoinositide substrates containing a 5-phosphate. In addition to hydrolyzing known substrates of 5PTase enzymes, At5PTase11 also hydrolyzes the 5-phosphate from phosphatidylinositol (3,5) bisphosphate. We also show that the At5PTase11 gene is regulated by abscisic acid, jasmonic acid, and auxin, suggesting a role for phosphoinositide action in these signal transduction pathways." @default.
- W2036698942 created "2016-06-24" @default.
- W2036698942 creator A5048535578 @default.
- W2036698942 creator A5066820425 @default.
- W2036698942 date "2004-06-01" @default.
- W2036698942 modified "2023-09-25" @default.
- W2036698942 title "Molecular Characterization of an Arabidopsis Gene Encoding a Phospholipid-Specific Inositol Polyphosphate 5-Phosphatase " @default.
- W2036698942 cites W167368066 @default.
- W2036698942 cites W1922099438 @default.
- W2036698942 cites W1963814857 @default.
- W2036698942 cites W1972327486 @default.
- W2036698942 cites W1982694978 @default.
- W2036698942 cites W1985764146 @default.
- W2036698942 cites W1987086612 @default.
- W2036698942 cites W1987255438 @default.
- W2036698942 cites W1988681396 @default.
- W2036698942 cites W1989171518 @default.
- W2036698942 cites W1990134601 @default.
- W2036698942 cites W1994016509 @default.
- W2036698942 cites W1994858858 @default.
- W2036698942 cites W1995774065 @default.
- W2036698942 cites W1996342641 @default.
- W2036698942 cites W2019759867 @default.
- W2036698942 cites W2020458186 @default.
- W2036698942 cites W2023543654 @default.
- W2036698942 cites W2027336549 @default.
- W2036698942 cites W2038696130 @default.
- W2036698942 cites W2045782185 @default.
- W2036698942 cites W2081778111 @default.
- W2036698942 cites W2083339597 @default.
- W2036698942 cites W2097617359 @default.
- W2036698942 cites W2103448964 @default.
- W2036698942 cites W2120237563 @default.
- W2036698942 cites W2124161425 @default.
- W2036698942 cites W2143436189 @default.
- W2036698942 cites W2153096212 @default.
- W2036698942 cites W2157263433 @default.
- W2036698942 cites W2324248632 @default.
- W2036698942 cites W306292651 @default.
- W2036698942 cites W4235281314 @default.
- W2036698942 cites W4239608272 @default.
- W2036698942 cites W4253840457 @default.
- W2036698942 cites W601732413 @default.
- W2036698942 doi "https://doi.org/10.1104/pp.104.040253" @default.
- W2036698942 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/514128" @default.
- W2036698942 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15181205" @default.
- W2036698942 hasPublicationYear "2004" @default.
- W2036698942 type Work @default.
- W2036698942 sameAs 2036698942 @default.
- W2036698942 citedByCount "59" @default.
- W2036698942 countsByYear W20366989422012 @default.
- W2036698942 countsByYear W20366989422013 @default.
- W2036698942 countsByYear W20366989422014 @default.
- W2036698942 countsByYear W20366989422018 @default.
- W2036698942 countsByYear W20366989422019 @default.
- W2036698942 countsByYear W20366989422020 @default.
- W2036698942 countsByYear W20366989422021 @default.
- W2036698942 countsByYear W20366989422022 @default.
- W2036698942 countsByYear W20366989422023 @default.
- W2036698942 crossrefType "journal-article" @default.
- W2036698942 hasAuthorship W2036698942A5048535578 @default.
- W2036698942 hasAuthorship W2036698942A5066820425 @default.
- W2036698942 hasBestOaLocation W20366989421 @default.
- W2036698942 hasConcept C104317684 @default.
- W2036698942 hasConcept C143065580 @default.
- W2036698942 hasConcept C163235415 @default.
- W2036698942 hasConcept C170493617 @default.
- W2036698942 hasConcept C178666793 @default.
- W2036698942 hasConcept C181199279 @default.
- W2036698942 hasConcept C2775988993 @default.
- W2036698942 hasConcept C2777132085 @default.
- W2036698942 hasConcept C2777427919 @default.
- W2036698942 hasConcept C2778038992 @default.
- W2036698942 hasConcept C2778618036 @default.
- W2036698942 hasConcept C2779080361 @default.
- W2036698942 hasConcept C2779491563 @default.
- W2036698942 hasConcept C2779591172 @default.
- W2036698942 hasConcept C2780610907 @default.
- W2036698942 hasConcept C55493867 @default.
- W2036698942 hasConcept C62478195 @default.
- W2036698942 hasConcept C86803240 @default.
- W2036698942 hasConcept C95444343 @default.
- W2036698942 hasConceptScore W2036698942C104317684 @default.
- W2036698942 hasConceptScore W2036698942C143065580 @default.
- W2036698942 hasConceptScore W2036698942C163235415 @default.
- W2036698942 hasConceptScore W2036698942C170493617 @default.
- W2036698942 hasConceptScore W2036698942C178666793 @default.
- W2036698942 hasConceptScore W2036698942C181199279 @default.
- W2036698942 hasConceptScore W2036698942C2775988993 @default.
- W2036698942 hasConceptScore W2036698942C2777132085 @default.
- W2036698942 hasConceptScore W2036698942C2777427919 @default.
- W2036698942 hasConceptScore W2036698942C2778038992 @default.
- W2036698942 hasConceptScore W2036698942C2778618036 @default.
- W2036698942 hasConceptScore W2036698942C2779080361 @default.
- W2036698942 hasConceptScore W2036698942C2779491563 @default.
- W2036698942 hasConceptScore W2036698942C2779591172 @default.
- W2036698942 hasConceptScore W2036698942C2780610907 @default.
- W2036698942 hasConceptScore W2036698942C55493867 @default.