FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2036699684> ?p ?o ?g. }

• W2036699684 endingPage "559" @default.
• W2036699684 startingPage "556" @default.
• W2036699684 abstract "BK polyomavirus-associated nephropathy (BKVAN) is an important cause of renal allograft loss. Immunosuppression therapy in renal transplant recipients can lead to the reactivation of latent BK polyomavirus (BKV) infection, leading to BK viruria and viremia. This single-center study aimed to clarify the association between quantitative measurement of BKV DNA and the progression of BKV infection, and secondly to identify the risk factors associated with the evolution of viruria to viremia. We retrospectively analyzed 266 patients who underwent renal transplantation in our center from October 2006 to February 2013. We examined the viral loads of BKV in urine and plasma by quantitative real-time polymerase chain reaction assay after screening all of the recipients by urinary sediment examination. BKVAN was diagnosed by histological examination with immunohistochemistry of the large T antigen in biopsy specimens. Overall, 22 recipients showed BK viruria alone, whereas 22 progressed to BK viremia, of which 6 patients were diagnosed with BKVAN. Among BKVAN patients, 2 cases progressed to graft loss at 59 months and 31 months after diagnosis, respectively. In BKVAN group, the plasma viral loads were significantly higher than those in viremia without nephropathy (P < .001). Multivariate analysis revealed that the evolution of viruria to viremia was associated with recipient age over 55 years (odds ratio, 32.08; 95% confidence interval, 2.1–489.5) and tacrolimus exposure (odds ratio, 11.98; 95% confidence interval, 1.34–107.04). The progression from viremia to BKVAN was strongly associated with increasing plasma viral loads for BKV DNA. The cutoff value of 1 × 104 copies/mL for plasma viral loads could differentiate between BKVAN and viremia alone. Further, recipient age over 55 years and tacrolimus exposure were independently associated with the evolution of viruria to viremia." @default.
• W2036699684 created "2016-06-24" @default.
• W2036699684 creator A5002181512 @default.
• W2036699684 creator A5026192414 @default.
• W2036699684 creator A5028703308 @default.
• W2036699684 creator A5037711521 @default.
• W2036699684 creator A5038413661 @default.
• W2036699684 creator A5045946902 @default.
• W2036699684 creator A5052112629 @default.
• W2036699684 creator A5053997136 @default.
• W2036699684 creator A5080785927 @default.
• W2036699684 creator A5088636462 @default.
• W2036699684 creator A5089874733 @default.
• W2036699684 date "2014-03-01" @default.
• W2036699684 modified "2023-10-10" @default.
• W2036699684 title "Association of DNA Amplification With Progress of BK Polyomavirus Infection and Nephropathy in Renal Transplant Recipients" @default.
• W2036699684 cites W1598779393 @default.
• W2036699684 cites W1788698477 @default.
• W2036699684 cites W1866109845 @default.
• W2036699684 cites W1965594537 @default.
• W2036699684 cites W1999672299 @default.
• W2036699684 cites W1999858293 @default.
• W2036699684 cites W2032304400 @default.
• W2036699684 cites W2088168913 @default.
• W2036699684 cites W2135813995 @default.
• W2036699684 cites W4234977807 @default.
• W2036699684 doi "https://doi.org/10.1016/j.transproceed.2013.11.114" @default.
• W2036699684 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24656011" @default.
• W2036699684 hasPublicationYear "2014" @default.
• W2036699684 type Work @default.
• W2036699684 sameAs 2036699684 @default.
• W2036699684 citedByCount "12" @default.
• W2036699684 countsByYear W20366996842015 @default.
• W2036699684 countsByYear W20366996842016 @default.
• W2036699684 countsByYear W20366996842017 @default.
• W2036699684 countsByYear W20366996842018 @default.
• W2036699684 countsByYear W20366996842019 @default.
• W2036699684 countsByYear W20366996842020 @default.
• W2036699684 countsByYear W20366996842021 @default.
• W2036699684 countsByYear W20366996842022 @default.
• W2036699684 countsByYear W20366996842023 @default.
• W2036699684 crossrefType "journal-article" @default.
• W2036699684 hasAuthorship W2036699684A5002181512 @default.
• W2036699684 hasAuthorship W2036699684A5026192414 @default.
• W2036699684 hasAuthorship W2036699684A5028703308 @default.
• W2036699684 hasAuthorship W2036699684A5037711521 @default.
• W2036699684 hasAuthorship W2036699684A5038413661 @default.
• W2036699684 hasAuthorship W2036699684A5045946902 @default.
• W2036699684 hasAuthorship W2036699684A5052112629 @default.
• W2036699684 hasAuthorship W2036699684A5053997136 @default.
• W2036699684 hasAuthorship W2036699684A5080785927 @default.
• W2036699684 hasAuthorship W2036699684A5088636462 @default.
• W2036699684 hasAuthorship W2036699684A5089874733 @default.
• W2036699684 hasConcept C126322002 @default.
• W2036699684 hasConcept C126894567 @default.
• W2036699684 hasConcept C134018914 @default.
• W2036699684 hasConcept C142462285 @default.
• W2036699684 hasConcept C156957248 @default.
• W2036699684 hasConcept C203014093 @default.
• W2036699684 hasConcept C2522874641 @default.
• W2036699684 hasConcept C2776185481 @default.
• W2036699684 hasConcept C2778199330 @default.
• W2036699684 hasConcept C2780252810 @default.
• W2036699684 hasConcept C2780303639 @default.
• W2036699684 hasConcept C2781184683 @default.
• W2036699684 hasConcept C2909675724 @default.
• W2036699684 hasConcept C2909782663 @default.
• W2036699684 hasConcept C2911091166 @default.
• W2036699684 hasConcept C44249647 @default.
• W2036699684 hasConcept C555293320 @default.
• W2036699684 hasConcept C71924100 @default.
• W2036699684 hasConcept C90924648 @default.
• W2036699684 hasConceptScore W2036699684C126322002 @default.
• W2036699684 hasConceptScore W2036699684C126894567 @default.
• W2036699684 hasConceptScore W2036699684C134018914 @default.
• W2036699684 hasConceptScore W2036699684C142462285 @default.
• W2036699684 hasConceptScore W2036699684C156957248 @default.
• W2036699684 hasConceptScore W2036699684C203014093 @default.
• W2036699684 hasConceptScore W2036699684C2522874641 @default.
• W2036699684 hasConceptScore W2036699684C2776185481 @default.
• W2036699684 hasConceptScore W2036699684C2778199330 @default.
• W2036699684 hasConceptScore W2036699684C2780252810 @default.
• W2036699684 hasConceptScore W2036699684C2780303639 @default.
• W2036699684 hasConceptScore W2036699684C2781184683 @default.
• W2036699684 hasConceptScore W2036699684C2909675724 @default.
• W2036699684 hasConceptScore W2036699684C2909782663 @default.
• W2036699684 hasConceptScore W2036699684C2911091166 @default.
• W2036699684 hasConceptScore W2036699684C44249647 @default.
• W2036699684 hasConceptScore W2036699684C555293320 @default.
• W2036699684 hasConceptScore W2036699684C71924100 @default.
• W2036699684 hasConceptScore W2036699684C90924648 @default.
• W2036699684 hasIssue "2" @default.
• W2036699684 hasLocation W20366996841 @default.
• W2036699684 hasLocation W20366996842 @default.
• W2036699684 hasOpenAccess W2036699684 @default.
• W2036699684 hasPrimaryLocation W20366996841 @default.
• W2036699684 hasRelatedWork W1993025430 @default.
• W2036699684 hasRelatedWork W2002753371 @default.

• next