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- W2036699777 abstract "This chapter first discusses individual abnormalities in myeloid disorders by chromosome order. It then describes biphenotypic and therapy-related abnormalities. The most common fuorescence in situ hybridization (FISH) abnormalities associated with hematological malignancies may be identified by FISH analysis as a panel of tests. Melodysplastic syndromes (MDS), acute myeloid leukemia (AML), myeloproliferative neoplasms (MPNs), multiple myeloma (MM) and non-Hodgkin lymphoma (NHL) are all examples where FISH panels of probes are useful in identifying common cytogenetic anomalies in a single test. Combining the most common abnormalities detectable by FISH analysis as a panel of tests is effective in terms of cost and laboratory time, and improves patient care by the identification of all possible known chromosomal abnormalities in a fast and relatively easy approach. Often these abnormalities are seen in conjunction with one another, rather than as a sole anomaly; therefore, the chapter provides examples of more than one abnormality per panel." @default.
- W2036699777 created "2016-06-24" @default.
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- W2036699777 date "2014-08-22" @default.
- W2036699777 modified "2023-10-16" @default.
- W2036699777 title "Recurrent FISH abnormalities in myeloid disorders" @default.
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- W2036699777 doi "https://doi.org/10.1002/9781118412602.ch29" @default.
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