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- W2036703279 abstract "Abstract Summary: True spherical capsules are formed by electrostatic polysaccharide interaction between chitosan and gellan gum via polyion complex (PIC) formation in aqueous solutions. Dropwise addition of a chitosan solution into the gellan solution gave spherical capsules whose outside surface was gellan and whose inside was chitosan (chitosan in ‐gellan out capsule). Conversely, the addition of gellan into chitosan yields chitosan out ‐gellan in capsules. SEM observation revealed a fibrous network spreading along the capsule membrane of the chitosan in ‐gellan out capsule. The releasing properties of the capsules were examined using low molecular weight substances and high molecular weight proteins. For low molecular weight substances, the releasing kinetics were affected by the attractive and repulsive interactions between the substances and the inside component of the capsule. The molecular weight of the encapsulated substances also affects the releasing kinetics. These results, together with a simple preparation procedure, indicate the applicability of chitosan‐gellan capsules as drug‐carrier materials having a controlling release mechanism. As an application example, preparation of an actually eatable artificial roe was also described. Illustrative drawing of PIC capsule formation. magnified image Illustrative drawing of PIC capsule formation." @default.
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- W2036703279 date "2004-01-01" @default.
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- W2036703279 title "Preparation and Characterization of Chitosan-Gellan Hybrid Capsules Formed by Self-Assembly at an Aqueous Solution Interface" @default.
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