Matches in SemOpenAlex for { <https://semopenalex.org/work/W2036707765> ?p ?o ?g. }
- W2036707765 endingPage "60" @default.
- W2036707765 startingPage "53" @default.
- W2036707765 abstract "Clinical observations suggest that genetic and immunologic disparity could be a factor in fecundity. The HLA system (HLA) is polymorphic and TLX (Trophoblast Lymphocyte Cross-Reactive), which is also polymorphic, seems to be linked to it. The immunologic hypothesis follows that excessive HLA and TLX-sharing could explain the rejection of a semi-allogenic blastocyst. Study objectives are therefore twofold; To determine whether or not there is significant HLA-sharing between spouses with unexplained recurrent spontaneous abortions (RSA) and to determine whether or not there is an association between some HLA specificities and RSA.The study includes only Caucasian couples that have had three successive spontaneous abortions. These were distributed in two groups: Group E: 18 couples either with known aetiology or with secondary RSA; Group U: seven couples with unexplained primary RSA; Control group C: 21 couples with at least two children and no spontaneous abortions. Tissue typing for HLA-A and B molecules was performed using serotyping methodology based on lymphocytotoxicity reaction. The different DRB1 alleles (class II) were determined by oligotyping with a non-radioactive reverse dot-blot methodology.Statistical comparison shows that the number of couples without shared specificity is not significantly different between the three groups for each locus independently and for the set of three. Our results show also that the allelic frequencies are not significantly different between the three groups.There is no higher HLA-sharing in couples with RSA than in fertile couples. Similarly, no particular HLA specificity can be associated with the RSA." @default.
- W2036707765 created "2016-06-24" @default.
- W2036707765 creator A5017160956 @default.
- W2036707765 creator A5025490201 @default.
- W2036707765 creator A5038639472 @default.
- W2036707765 creator A5050585732 @default.
- W2036707765 creator A5057031165 @default.
- W2036707765 creator A5075112000 @default.
- W2036707765 date "1995-05-01" @default.
- W2036707765 modified "2023-10-16" @default.
- W2036707765 title "Immunogenetic study of couples with recurrent spontaneous abortions" @default.
- W2036707765 cites W1488153193 @default.
- W2036707765 cites W1928658893 @default.
- W2036707765 cites W1963610024 @default.
- W2036707765 cites W1964451626 @default.
- W2036707765 cites W1967256263 @default.
- W2036707765 cites W1968232306 @default.
- W2036707765 cites W1975506317 @default.
- W2036707765 cites W1986672594 @default.
- W2036707765 cites W1987772994 @default.
- W2036707765 cites W1988318122 @default.
- W2036707765 cites W2010920010 @default.
- W2036707765 cites W2015800825 @default.
- W2036707765 cites W2021649985 @default.
- W2036707765 cites W2026461518 @default.
- W2036707765 cites W2028875161 @default.
- W2036707765 cites W2052370034 @default.
- W2036707765 cites W2053822433 @default.
- W2036707765 cites W2070766223 @default.
- W2036707765 cites W2092272606 @default.
- W2036707765 cites W2118094114 @default.
- W2036707765 cites W2130117368 @default.
- W2036707765 cites W2201037520 @default.
- W2036707765 cites W2259512671 @default.
- W2036707765 cites W2336575980 @default.
- W2036707765 cites W2401993632 @default.
- W2036707765 cites W2403045550 @default.
- W2036707765 cites W2416793735 @default.
- W2036707765 cites W2418965245 @default.
- W2036707765 cites W2423582612 @default.
- W2036707765 cites W2424516818 @default.
- W2036707765 cites W2470539096 @default.
- W2036707765 cites W3492911 @default.
- W2036707765 cites W2405420608 @default.
- W2036707765 doi "https://doi.org/10.1016/0028-2243(95)02076-4" @default.
- W2036707765 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7635232" @default.
- W2036707765 hasPublicationYear "1995" @default.
- W2036707765 type Work @default.
- W2036707765 sameAs 2036707765 @default.
- W2036707765 citedByCount "4" @default.
- W2036707765 countsByYear W20367077652015 @default.
- W2036707765 crossrefType "journal-article" @default.
- W2036707765 hasAuthorship W2036707765A5017160956 @default.
- W2036707765 hasAuthorship W2036707765A5025490201 @default.
- W2036707765 hasAuthorship W2036707765A5038639472 @default.
- W2036707765 hasAuthorship W2036707765A5050585732 @default.
- W2036707765 hasAuthorship W2036707765A5057031165 @default.
- W2036707765 hasAuthorship W2036707765A5075112000 @default.
- W2036707765 hasConcept C104317684 @default.
- W2036707765 hasConcept C147483822 @default.
- W2036707765 hasConcept C180754005 @default.
- W2036707765 hasConcept C188280979 @default.
- W2036707765 hasConcept C203014093 @default.
- W2036707765 hasConcept C2776090121 @default.
- W2036707765 hasConcept C2778740727 @default.
- W2036707765 hasConcept C2781209916 @default.
- W2036707765 hasConcept C54355233 @default.
- W2036707765 hasConcept C71924100 @default.
- W2036707765 hasConcept C86803240 @default.
- W2036707765 hasConcept C8891405 @default.
- W2036707765 hasConceptScore W2036707765C104317684 @default.
- W2036707765 hasConceptScore W2036707765C147483822 @default.
- W2036707765 hasConceptScore W2036707765C180754005 @default.
- W2036707765 hasConceptScore W2036707765C188280979 @default.
- W2036707765 hasConceptScore W2036707765C203014093 @default.
- W2036707765 hasConceptScore W2036707765C2776090121 @default.
- W2036707765 hasConceptScore W2036707765C2778740727 @default.
- W2036707765 hasConceptScore W2036707765C2781209916 @default.
- W2036707765 hasConceptScore W2036707765C54355233 @default.
- W2036707765 hasConceptScore W2036707765C71924100 @default.
- W2036707765 hasConceptScore W2036707765C86803240 @default.
- W2036707765 hasConceptScore W2036707765C8891405 @default.
- W2036707765 hasIssue "1" @default.
- W2036707765 hasLocation W20367077651 @default.
- W2036707765 hasLocation W20367077652 @default.
- W2036707765 hasOpenAccess W2036707765 @default.
- W2036707765 hasPrimaryLocation W20367077651 @default.
- W2036707765 hasRelatedWork W1989613103 @default.
- W2036707765 hasRelatedWork W1990329984 @default.
- W2036707765 hasRelatedWork W1991211153 @default.
- W2036707765 hasRelatedWork W1997924220 @default.
- W2036707765 hasRelatedWork W2021502563 @default.
- W2036707765 hasRelatedWork W2041626124 @default.
- W2036707765 hasRelatedWork W2067167938 @default.
- W2036707765 hasRelatedWork W2091857464 @default.
- W2036707765 hasRelatedWork W2121743997 @default.
- W2036707765 hasRelatedWork W69427483 @default.
- W2036707765 hasVolume "60" @default.