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- W2036714294 abstract "Authors investigated the circumstantial evidence for autoimmunity in schizophrenia patients of Siliguri by considering the immune parameters like HLA Class I genes, IL-2 and IL6 and T cell subsets. Low resolution PCR-SSP method was applied for typing the HLA genes. Serum levels of IL-2 and IL-6 were measured by ELISA method. The CD4+ and CD8+ subset count were done using flow cytometry. A significant increase in HLA A*03 gene was observed in patients along with the significant decrease of HLA-A*31 and HLA-B*51. Both IL-2 and IL-6 were found to have decreased levels in the patients. Although the mean percentage of CD4+ and CD8+ cells was higher in patients but not significantly higher than controls. These cumulative preliminary findings are suggestive of alterations in the immune system of schizophrenia patients of this region." @default.
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- W2036714294 date "2011-12-01" @default.
- W2036714294 modified "2023-09-26" @default.
- W2036714294 title "Immunomodulation in schizophrenia: A study among the Indian schizophrenia patients of Siliguri, West Bengal" @default.
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- W2036714294 doi "https://doi.org/10.1016/j.ajp.2011.08.002" @default.
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