Matches in SemOpenAlex for { <https://semopenalex.org/work/W2036715714> ?p ?o ?g. }
Showing items 1 to 97 of
97
with 100 items per page.
- W2036715714 abstract "The levels of PLCgamma, a phospholipase C (PLC) isozyme, were higher in the cytosol fraction than in the membrane fraction in several control brain regions. The levels of PLCgamma were significantly elevated in the membrane, but not in the cytosolic fraction of the hippocampus of AD subjects. In the superior and middle temporal gyri (SMTG) of AD subjects, the levels of PLCgamma were significantly elevated in both the membrane and cytosolic fractions. In the inferior parietal lobule and cerebellum of AD subjects, no significant changes were found in the PLCgamma levels of either cytosolic or membrane fractions. These results suggest that the increased levels of PLCgamma, by increasing the hydrolysis of PIP2 in the hippocampus and SMTG, may contribute to pathophysiology of AD. These results also support a role for excitatory neurotransmitters and their receptors in AD." @default.
- W2036715714 created "2016-06-24" @default.
- W2036715714 creator A5001988202 @default.
- W2036715714 creator A5028166500 @default.
- W2036715714 creator A5052496530 @default.
- W2036715714 creator A5065589335 @default.
- W2036715714 date "1998-11-01" @default.
- W2036715714 modified "2023-10-16" @default.
- W2036715714 title "Regional levels of brain phospholipase Cγ in Alzheimer's disease" @default.
- W2036715714 cites W1491358295 @default.
- W2036715714 cites W1506990787 @default.
- W2036715714 cites W1537006910 @default.
- W2036715714 cites W1743329534 @default.
- W2036715714 cites W1972152590 @default.
- W2036715714 cites W1994151063 @default.
- W2036715714 cites W1995954863 @default.
- W2036715714 cites W2000959134 @default.
- W2036715714 cites W2002946658 @default.
- W2036715714 cites W2046213715 @default.
- W2036715714 cites W2049192526 @default.
- W2036715714 cites W2049262684 @default.
- W2036715714 cites W2054095601 @default.
- W2036715714 cites W2059148729 @default.
- W2036715714 cites W2062034622 @default.
- W2036715714 cites W2082761279 @default.
- W2036715714 cites W2281694448 @default.
- W2036715714 cites W35662498 @default.
- W2036715714 doi "https://doi.org/10.1016/s0006-8993(98)00935-4" @default.
- W2036715714 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9804940" @default.
- W2036715714 hasPublicationYear "1998" @default.
- W2036715714 type Work @default.
- W2036715714 sameAs 2036715714 @default.
- W2036715714 citedByCount "14" @default.
- W2036715714 countsByYear W20367157142012 @default.
- W2036715714 countsByYear W20367157142014 @default.
- W2036715714 countsByYear W20367157142015 @default.
- W2036715714 countsByYear W20367157142018 @default.
- W2036715714 countsByYear W20367157142020 @default.
- W2036715714 crossrefType "journal-article" @default.
- W2036715714 hasAuthorship W2036715714A5001988202 @default.
- W2036715714 hasAuthorship W2036715714A5028166500 @default.
- W2036715714 hasAuthorship W2036715714A5052496530 @default.
- W2036715714 hasAuthorship W2036715714A5065589335 @default.
- W2036715714 hasConcept C112592302 @default.
- W2036715714 hasConcept C126322002 @default.
- W2036715714 hasConcept C12927208 @default.
- W2036715714 hasConcept C134018914 @default.
- W2036715714 hasConcept C169760540 @default.
- W2036715714 hasConcept C170493617 @default.
- W2036715714 hasConcept C181199279 @default.
- W2036715714 hasConcept C185592680 @default.
- W2036715714 hasConcept C2776551241 @default.
- W2036715714 hasConcept C2778597717 @default.
- W2036715714 hasConcept C2779134260 @default.
- W2036715714 hasConcept C2779652256 @default.
- W2036715714 hasConcept C2781161787 @default.
- W2036715714 hasConcept C502032728 @default.
- W2036715714 hasConcept C55493867 @default.
- W2036715714 hasConcept C71924100 @default.
- W2036715714 hasConcept C86803240 @default.
- W2036715714 hasConcept C98539663 @default.
- W2036715714 hasConceptScore W2036715714C112592302 @default.
- W2036715714 hasConceptScore W2036715714C126322002 @default.
- W2036715714 hasConceptScore W2036715714C12927208 @default.
- W2036715714 hasConceptScore W2036715714C134018914 @default.
- W2036715714 hasConceptScore W2036715714C169760540 @default.
- W2036715714 hasConceptScore W2036715714C170493617 @default.
- W2036715714 hasConceptScore W2036715714C181199279 @default.
- W2036715714 hasConceptScore W2036715714C185592680 @default.
- W2036715714 hasConceptScore W2036715714C2776551241 @default.
- W2036715714 hasConceptScore W2036715714C2778597717 @default.
- W2036715714 hasConceptScore W2036715714C2779134260 @default.
- W2036715714 hasConceptScore W2036715714C2779652256 @default.
- W2036715714 hasConceptScore W2036715714C2781161787 @default.
- W2036715714 hasConceptScore W2036715714C502032728 @default.
- W2036715714 hasConceptScore W2036715714C55493867 @default.
- W2036715714 hasConceptScore W2036715714C71924100 @default.
- W2036715714 hasConceptScore W2036715714C86803240 @default.
- W2036715714 hasConceptScore W2036715714C98539663 @default.
- W2036715714 hasLocation W20367157141 @default.
- W2036715714 hasLocation W20367157142 @default.
- W2036715714 hasOpenAccess W2036715714 @default.
- W2036715714 hasPrimaryLocation W20367157141 @default.
- W2036715714 hasRelatedWork W1991750851 @default.
- W2036715714 hasRelatedWork W2009521550 @default.
- W2036715714 hasRelatedWork W2033526006 @default.
- W2036715714 hasRelatedWork W2036715714 @default.
- W2036715714 hasRelatedWork W2038070379 @default.
- W2036715714 hasRelatedWork W2054660343 @default.
- W2036715714 hasRelatedWork W2064318241 @default.
- W2036715714 hasRelatedWork W2079860336 @default.
- W2036715714 hasRelatedWork W2133641226 @default.
- W2036715714 hasRelatedWork W2287959475 @default.
- W2036715714 isParatext "false" @default.
- W2036715714 isRetracted "false" @default.
- W2036715714 magId "2036715714" @default.
- W2036715714 workType "article" @default.