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• W2036719275 abstract "1. 1. Marked temperature dependence of impulse activity is a property of mammalian neurons which are mainly localized in the hypothalamus and adjoining brain regions. 2. 2. Data is presented on the similarity of thermal behaviour of neurons in vivo and in vitro . It follows from the evidence on the synaptic blockade, postnatal development, and intracellular recordings that inherent thermosensitivity is a property primarily of warm-sensitive hypothalamic neurons. 3. 3. The Na + /K + pump does not underlie hypothalamic neuron thermosensitivity. Warm-sensitive units possess highly thermosensitive non-inactivating inward sodium current. 4. 4. Data is presented on thermo-induced membrane structural rearrangements based on changes in the physical state of lipids, changes in protein conformation and membrane skeleton activity. A hypothesis of the relation of threshold temperature responses of warm sensitive hypothalamic neurons with these membrane phenomena, as well as alternative hypotheses, are viewed." @default.
• W2036719275 created "2016-06-24" @default.
• W2036719275 creator A5002201499 @default.
• W2036719275 date "1994-08-01" @default.
• W2036719275 modified "2023-09-25" @default.
• W2036719275 title "Thermosensitivity: An intrinsic property of hypothalamic neurons" @default.
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• W2036719275 doi "https://doi.org/10.1016/0306-4565(94)90045-0" @default.
• W2036719275 hasPublicationYear "1994" @default.
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