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- W2036735306 abstract "We are writing to request correction of an error in Class Assignment and recommendation wording made in the recently published 2014 secondary stroke prevention guideline.1 The guideline assigns to patent foramen ovale (PFO) device closure treatment a Class III assignment and wording. But the evidence reviewed by the Committee supports a Class IIb, not Class III, recommendation and wording.We think the Committee was led astray by a recent change in American Heart Association (AHA) levels of evidence procedures. In the past, AHA/American College of Cardiology (ACC)/American Stroke Association (ASA) Class III, level of evidence (LOE) A recommendations were reserved for cases in which multiple clinical trials clearly demonstrated definite harm from an intervention. However, recently, the AHA/ACC/ASA revised its evidence table to also permit Class III, LOE A recommendations when evidence demonstrates that an intervention confers no benefit. Guideline writers are likely not yet familiar with the types of trials needed to support such a finding of absence of benefit. The evidence reviewed by the committee does not support a finding of No Benefit per the AHA/ACC/ASA evidentiary table.The standard evidence-based medicine requirement for a No …" @default.
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- W2036735306 date "2015-04-01" @default.
- W2036735306 modified "2023-10-17" @default.
- W2036735306 title "Letter by Saver et al Regarding Article, “Guidelines for the Prevention of Stroke in Patients With Stroke and Transient Ischemic Attack: A Guideline for Healthcare Professionals From the American Heart Association/American Stroke Association”" @default.
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- W2036735306 doi "https://doi.org/10.1161/strokeaha.115.007311" @default.
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