Matches in SemOpenAlex for { <https://semopenalex.org/work/W2036749312> ?p ?o ?g. }
- W2036749312 endingPage "1523" @default.
- W2036749312 startingPage "1519" @default.
- W2036749312 abstract "Administration of corticosterone (10 mg/kg, ip, twice daily for 3 days) to mice during the second week of postnatal development led to an increase of tyrosine hydroxylase (TH) activity in the locus coeruleus, but not in the substantia nigra. The corticosterone effect was observed only transiently during this developmental period. Tritiated corticosterone can bind to a cytosol fraction prepared from mouse locus coeruleus, with a specific binding capacity of 110 fmol/mg protein. There is a correlation between the ability of various steroids to increase TH activity and their binding to the cytosol glucocorticoid receptor. Cortexolone and progesterone, two antiglucocorticoids that can bind to the cytosol receptor, were found to abolish the effect of corticosterone in increasing TH activity. It appears that the noradrenergic neurons in the locus coeruleus may be target cells for glucocorticoids, and that the glucocorticoid effect on TH may be by a receptor-mediated mechanism." @default.
- W2036749312 created "2016-06-24" @default.
- W2036749312 creator A5028553238 @default.
- W2036749312 creator A5040975973 @default.
- W2036749312 creator A5063435300 @default.
- W2036749312 date "1982-11-01" @default.
- W2036749312 modified "2023-09-23" @default.
- W2036749312 title "Glucocorticoid Influence on Tyrosine Hydroxylase Activity in Mouse Locus Coeruleus during Postnatal Development*" @default.
- W2036749312 cites W123942096 @default.
- W2036749312 cites W1500057643 @default.
- W2036749312 cites W1775749144 @default.
- W2036749312 cites W1794404804 @default.
- W2036749312 cites W1972658372 @default.
- W2036749312 cites W1975573822 @default.
- W2036749312 cites W1977501674 @default.
- W2036749312 cites W1997699020 @default.
- W2036749312 cites W1998270089 @default.
- W2036749312 cites W2001103357 @default.
- W2036749312 cites W2003092157 @default.
- W2036749312 cites W2009177010 @default.
- W2036749312 cites W2010589580 @default.
- W2036749312 cites W2033506746 @default.
- W2036749312 cites W2045535163 @default.
- W2036749312 cites W2045584673 @default.
- W2036749312 cites W2054496266 @default.
- W2036749312 cites W2056541108 @default.
- W2036749312 cites W2057903494 @default.
- W2036749312 cites W2058982518 @default.
- W2036749312 cites W2070083696 @default.
- W2036749312 cites W2070356199 @default.
- W2036749312 cites W2087674088 @default.
- W2036749312 cites W2123164383 @default.
- W2036749312 cites W2154463038 @default.
- W2036749312 cites W2158771872 @default.
- W2036749312 cites W2161213045 @default.
- W2036749312 cites W2293556558 @default.
- W2036749312 doi "https://doi.org/10.1210/endo-111-5-1519" @default.
- W2036749312 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6127203" @default.
- W2036749312 hasPublicationYear "1982" @default.
- W2036749312 type Work @default.
- W2036749312 sameAs 2036749312 @default.
- W2036749312 citedByCount "56" @default.
- W2036749312 countsByYear W20367493122014 @default.
- W2036749312 countsByYear W20367493122015 @default.
- W2036749312 countsByYear W20367493122016 @default.
- W2036749312 countsByYear W20367493122017 @default.
- W2036749312 countsByYear W20367493122018 @default.
- W2036749312 countsByYear W20367493122021 @default.
- W2036749312 crossrefType "journal-article" @default.
- W2036749312 hasAuthorship W2036749312A5028553238 @default.
- W2036749312 hasAuthorship W2036749312A5040975973 @default.
- W2036749312 hasAuthorship W2036749312A5063435300 @default.
- W2036749312 hasConcept C126322002 @default.
- W2036749312 hasConcept C132154277 @default.
- W2036749312 hasConcept C134018914 @default.
- W2036749312 hasConcept C159167319 @default.
- W2036749312 hasConcept C170493617 @default.
- W2036749312 hasConcept C181199279 @default.
- W2036749312 hasConcept C185592680 @default.
- W2036749312 hasConcept C2775894120 @default.
- W2036749312 hasConcept C2776491826 @default.
- W2036749312 hasConcept C2778468602 @default.
- W2036749312 hasConcept C2780352252 @default.
- W2036749312 hasConcept C2780841215 @default.
- W2036749312 hasConcept C513476851 @default.
- W2036749312 hasConcept C529278444 @default.
- W2036749312 hasConcept C55493867 @default.
- W2036749312 hasConcept C59493245 @default.
- W2036749312 hasConcept C71315377 @default.
- W2036749312 hasConcept C71924100 @default.
- W2036749312 hasConcept C86803240 @default.
- W2036749312 hasConcept C98539663 @default.
- W2036749312 hasConceptScore W2036749312C126322002 @default.
- W2036749312 hasConceptScore W2036749312C132154277 @default.
- W2036749312 hasConceptScore W2036749312C134018914 @default.
- W2036749312 hasConceptScore W2036749312C159167319 @default.
- W2036749312 hasConceptScore W2036749312C170493617 @default.
- W2036749312 hasConceptScore W2036749312C181199279 @default.
- W2036749312 hasConceptScore W2036749312C185592680 @default.
- W2036749312 hasConceptScore W2036749312C2775894120 @default.
- W2036749312 hasConceptScore W2036749312C2776491826 @default.
- W2036749312 hasConceptScore W2036749312C2778468602 @default.
- W2036749312 hasConceptScore W2036749312C2780352252 @default.
- W2036749312 hasConceptScore W2036749312C2780841215 @default.
- W2036749312 hasConceptScore W2036749312C513476851 @default.
- W2036749312 hasConceptScore W2036749312C529278444 @default.
- W2036749312 hasConceptScore W2036749312C55493867 @default.
- W2036749312 hasConceptScore W2036749312C59493245 @default.
- W2036749312 hasConceptScore W2036749312C71315377 @default.
- W2036749312 hasConceptScore W2036749312C71924100 @default.
- W2036749312 hasConceptScore W2036749312C86803240 @default.
- W2036749312 hasConceptScore W2036749312C98539663 @default.
- W2036749312 hasIssue "5" @default.
- W2036749312 hasLocation W20367493121 @default.
- W2036749312 hasLocation W20367493122 @default.
- W2036749312 hasOpenAccess W2036749312 @default.
- W2036749312 hasPrimaryLocation W20367493121 @default.
- W2036749312 hasRelatedWork W2005344166 @default.