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• W2036764088 endingPage "495" @default.
• W2036764088 startingPage "475" @default.
• W2036764088 abstract "House dust mite allergens from the Pyroglyphidae family are one of the most frequent and potent causes of allergic sensitatisation. Since 1988, molecular knowledge has increased considerably and structures and functions have been determined for most of them.Of the 22 defined allergens, the major IgE-binding has been reported for groups 1 and 2 accounting for 40-60% of the anti-house dust mite titres. Der p 1, 2, 4, 5, 7 allergens account for about 80% of the IgE-response. Der p 4, 5, 7, 11, 14, 15 have a prevalence of sensitization of about 10% each. The IgE-binding to groups 3, 8, 10, 20 is low. Most of the allergens can be identified by amino-acid sequences and the tertiary structures of the major allergens have been solved. Most allergens are proteolytic enzymes: Der p1 for instance is a cysteine protease. Der p 2 has structural homology with MD-2, a co-receptor of the Toll-like receptor (TLR4) whose ligand is LPS. Knowledge of the structure of mite allergens has allowed better interpretation of cross-reactions between allergens from the same family or from more distant families.From a practical point of view: the occurrence of multisensitisation is better explained and molecular epidemiology has allowed a better choice of allergen molecules useful for diagnosis. Finally, new concepts of immunotherapy based on genetically engineered hypoallergenic variants of major allergens, used alone or in combination, may lead to useful therapeutic approach." @default.
• W2036764088 created "2016-06-24" @default.
• W2036764088 creator A5054661531 @default.
• W2036764088 creator A5086254885 @default.
• W2036764088 date "2011-04-01" @default.
• W2036764088 modified "2023-10-14" @default.
• W2036764088 title "Les acariens domestiques et leurs allergènes" @default.
• W2036764088 cites W1489193873 @default.
• W2036764088 cites W1491240040 @default.
• W2036764088 cites W1502135892 @default.
• W2036764088 cites W1556888365 @default.
• W2036764088 cites W1583081002 @default.
• W2036764088 cites W1642728877 @default.
• W2036764088 cites W1720358490 @default.
• W2036764088 cites W1752886302 @default.
• W2036764088 cites W1811719059 @default.
• W2036764088 cites W1963608069 @default.
• W2036764088 cites W1965474612 @default.
• W2036764088 cites W1966108601 @default.
• W2036764088 cites W1968608814 @default.
• W2036764088 cites W1969528905 @default.
• W2036764088 cites W1972810556 @default.
• W2036764088 cites W1973876782 @default.
• W2036764088 cites W1975190212 @default.
• W2036764088 cites W1977008844 @default.
• W2036764088 cites W1977355942 @default.
• W2036764088 cites W1979858563 @default.
• W2036764088 cites W1981156415 @default.
• W2036764088 cites W1983714532 @default.
• W2036764088 cites W1985387378 @default.
• W2036764088 cites W1985428412 @default.
• W2036764088 cites W1986838519 @default.
• W2036764088 cites W1987925923 @default.
• W2036764088 cites W1991645244 @default.
• W2036764088 cites W1992035124 @default.
• W2036764088 cites W1992629205 @default.
• W2036764088 cites W1995533886 @default.
• W2036764088 cites W1996955331 @default.
• W2036764088 cites W2001486104 @default.
• W2036764088 cites W2002126149 @default.
• W2036764088 cites W2003952585 @default.
• W2036764088 cites W2004476337 @default.
• W2036764088 cites W2004492373 @default.
• W2036764088 cites W2005152741 @default.
• W2036764088 cites W2007470727 @default.
• W2036764088 cites W2011436753 @default.
• W2036764088 cites W2012405469 @default.
• W2036764088 cites W2013141036 @default.
• W2036764088 cites W2013762452 @default.
• W2036764088 cites W2015853656 @default.
• W2036764088 cites W2017899176 @default.
• W2036764088 cites W2021675393 @default.
• W2036764088 cites W2022972217 @default.
• W2036764088 cites W2024249282 @default.
• W2036764088 cites W2025137333 @default.
• W2036764088 cites W2026909435 @default.
• W2036764088 cites W2027302925 @default.
• W2036764088 cites W2027489995 @default.
• W2036764088 cites W2029227524 @default.
• W2036764088 cites W2029478951 @default.
• W2036764088 cites W2030442464 @default.
• W2036764088 cites W2031473217 @default.
• W2036764088 cites W2031977904 @default.
• W2036764088 cites W2033056542 @default.
• W2036764088 cites W2033413877 @default.
• W2036764088 cites W2033730911 @default.
• W2036764088 cites W2035215972 @default.
• W2036764088 cites W2035538568 @default.
• W2036764088 cites W2035821609 @default.
• W2036764088 cites W2037019085 @default.
• W2036764088 cites W2039680586 @default.
• W2036764088 cites W2041787219 @default.
• W2036764088 cites W2041891125 @default.
• W2036764088 cites W2043741683 @default.
• W2036764088 cites W2044723459 @default.
• W2036764088 cites W2047094561 @default.
• W2036764088 cites W2049463019 @default.
• W2036764088 cites W2049687832 @default.
• W2036764088 cites W2050794863 @default.
• W2036764088 cites W2052290049 @default.
• W2036764088 cites W2054386434 @default.
• W2036764088 cites W2054724837 @default.
• W2036764088 cites W2055967666 @default.
• W2036764088 cites W2056717140 @default.
• W2036764088 cites W2057723468 @default.
• W2036764088 cites W2058454512 @default.
• W2036764088 cites W2059359155 @default.
• W2036764088 cites W2065905934 @default.
• W2036764088 cites W2066203499 @default.
• W2036764088 cites W2068675062 @default.
• W2036764088 cites W2068751104 @default.
• W2036764088 cites W2072382347 @default.
• W2036764088 cites W2074389578 @default.
• W2036764088 cites W2076670706 @default.
• W2036764088 cites W2077805638 @default.
• W2036764088 cites W2081224914 @default.
• W2036764088 cites W2081702646 @default.
• W2036764088 cites W2082897316 @default.

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