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• W2036778381 abstract "Background/Aims: Evidence has pointed to the role of sphingosine in cellular differentiation, cell growth, and apoptosis. The present study investigated sphingosine-induced apoptosis in human gastric cancer cells. Methods: Well differentiated MKN-28 and poorly differentiated MKN-45 human gastric cancer cells were cultured. MTT assay, TUNEL staining, Western blotting, and assay of caspase-3, -8, and -9 activities were carried out in cells transfected with and without the siRNA to silence the protein kinase C (PKC)-δ-targeted gene. Results: Sphingosine induced apoptosis in MKN-28 cells, with the potential much" @default.
• W2036778381 created "2016-06-24" @default.
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• W2036778381 date "2012-01-01" @default.
• W2036778381 modified "2023-10-02" @default.
• W2036778381 title "Sphingosine Induces Apoptosis in MKN-28 Human Gastric Cancer Cells in an SDK-Dependent Manner" @default.
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• W2036778381 doi "https://doi.org/10.1159/000341475" @default.
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