Matches in SemOpenAlex for { <https://semopenalex.org/work/W2036778846> ?p ?o ?g. }
Showing items 1 to 79 of
79
with 100 items per page.
- W2036778846 endingPage "153" @default.
- W2036778846 startingPage "153" @default.
- W2036778846 abstract "Comparison of preference and safety of powder and liquid lactulose in adult patients with chronic constipation Charles F Barish1, Bryan Voss2, Byron Kaelin21Wake Research Associates, Raleigh, North Carolina, USA; 2Cumberland Pharmaceuticals Inc., Nashville, Tennessee, USABackground: Chronic constipation is an important clinical condition which can result in serious discomfort and even require hospitalization. Powder and liquid lactulose are designated as clinically equivalent for the treatment of constipation, but there are significant differences in the taste, consistency, and portability of the products, which may affect patient compliance and therefore clinical outcome.Aim: To evaluate patient preference between powder and liquid lactulose in terms of overall preference, taste, consistency, and portability, and safety in terms of adverse events.Methods: Three sites randomized patients (total n = 50) to powder or liquid lactulose for seven days with crossover. Patient preference was assessed by a questionnaire, and the occurrence of adverse events was monitored.Results: Of those expressing a preference, 44% and 57% more patients preferred the taste and consistency, respectively, of powder over liquid lactulose. More than six times as many patients preferred the portability of powder compared with liquid lactulose and, overall, 77% more patients preferred powder over liquid lactulose. There was no difference between treatment groups in terms of adverse events (P = 0.635).Conclusions: More patients preferred powder compared with liquid lactulose and the products were equally safe. These findings may impact patient compliance, and therefore may affect clinical outcome.Keywords: constipation, lactulose, laxative" @default.
- W2036778846 created "2016-06-24" @default.
- W2036778846 creator A5060305338 @default.
- W2036778846 creator A5062218070 @default.
- W2036778846 creator A5090495484 @default.
- W2036778846 date "2010-10-01" @default.
- W2036778846 modified "2023-09-28" @default.
- W2036778846 title "Comparison of preference and safety of powder and liquid lactulose in adult patients with chronic constipation" @default.
- W2036778846 cites W1921373566 @default.
- W2036778846 cites W1974465804 @default.
- W2036778846 cites W1983035974 @default.
- W2036778846 cites W1994971197 @default.
- W2036778846 cites W2023575592 @default.
- W2036778846 cites W2028220706 @default.
- W2036778846 cites W2028938951 @default.
- W2036778846 cites W2044931055 @default.
- W2036778846 cites W2795974931 @default.
- W2036778846 cites W2799858327 @default.
- W2036778846 cites W2169511487 @default.
- W2036778846 doi "https://doi.org/10.2147/ceg.s13568" @default.
- W2036778846 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3108673" @default.
- W2036778846 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21694860" @default.
- W2036778846 hasPublicationYear "2010" @default.
- W2036778846 type Work @default.
- W2036778846 sameAs 2036778846 @default.
- W2036778846 citedByCount "3" @default.
- W2036778846 countsByYear W20367788462012 @default.
- W2036778846 countsByYear W20367788462019 @default.
- W2036778846 crossrefType "journal-article" @default.
- W2036778846 hasAuthorship W2036778846A5060305338 @default.
- W2036778846 hasAuthorship W2036778846A5062218070 @default.
- W2036778846 hasAuthorship W2036778846A5090495484 @default.
- W2036778846 hasBestOaLocation W20367788461 @default.
- W2036778846 hasConcept C126322002 @default.
- W2036778846 hasConcept C142724271 @default.
- W2036778846 hasConcept C197934379 @default.
- W2036778846 hasConcept C204787440 @default.
- W2036778846 hasConcept C27081682 @default.
- W2036778846 hasConcept C2777448540 @default.
- W2036778846 hasConcept C2778375690 @default.
- W2036778846 hasConcept C2780661987 @default.
- W2036778846 hasConcept C2781112942 @default.
- W2036778846 hasConcept C535046627 @default.
- W2036778846 hasConcept C71924100 @default.
- W2036778846 hasConcept C87813604 @default.
- W2036778846 hasConceptScore W2036778846C126322002 @default.
- W2036778846 hasConceptScore W2036778846C142724271 @default.
- W2036778846 hasConceptScore W2036778846C197934379 @default.
- W2036778846 hasConceptScore W2036778846C204787440 @default.
- W2036778846 hasConceptScore W2036778846C27081682 @default.
- W2036778846 hasConceptScore W2036778846C2777448540 @default.
- W2036778846 hasConceptScore W2036778846C2778375690 @default.
- W2036778846 hasConceptScore W2036778846C2780661987 @default.
- W2036778846 hasConceptScore W2036778846C2781112942 @default.
- W2036778846 hasConceptScore W2036778846C535046627 @default.
- W2036778846 hasConceptScore W2036778846C71924100 @default.
- W2036778846 hasConceptScore W2036778846C87813604 @default.
- W2036778846 hasLocation W20367788461 @default.
- W2036778846 hasLocation W20367788462 @default.
- W2036778846 hasLocation W20367788463 @default.
- W2036778846 hasLocation W20367788464 @default.
- W2036778846 hasOpenAccess W2036778846 @default.
- W2036778846 hasPrimaryLocation W20367788461 @default.
- W2036778846 hasRelatedWork W1516221174 @default.
- W2036778846 hasRelatedWork W1993226188 @default.
- W2036778846 hasRelatedWork W2071102937 @default.
- W2036778846 hasRelatedWork W2122067858 @default.
- W2036778846 hasRelatedWork W2125665617 @default.
- W2036778846 hasRelatedWork W2371637389 @default.
- W2036778846 hasRelatedWork W2463375683 @default.
- W2036778846 hasRelatedWork W2601791777 @default.
- W2036778846 hasRelatedWork W4291790229 @default.
- W2036778846 hasRelatedWork W2185270745 @default.
- W2036778846 isParatext "false" @default.
- W2036778846 isRetracted "false" @default.
- W2036778846 magId "2036778846" @default.
- W2036778846 workType "article" @default.