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- W2036869229 abstract "Competition for palatable food or fluids within groups of rats has been previously used to mirror intra-group ranking. The paradigm of competition for sucrose pellets in non-food-deprived male Wistar rats was here extended from triads to tetrads aiming at evaluating whether the number of poor-performing rats, those animals being likely to model aspects of human psychopathologies (anxiety/depression/social withdrawal), could be increased. To evaluate potential superiority over the previously used Wistar strain, establishment and stability of the ranking was also assessed in tetrads of male Fischer and Sprague-Dawley rats. Clear and stable rank orders were seen in around 60-70% of both triads and tetrads of Wistar rats: a high-performing, a medium-performing and one (in triads) or two (in tetrads) poor-performing rats were identifiable, indicating that the number of poor-performing rats had increased in tetrads. Comparable rank orders were also seen in tetrads of Fischer and Sprague-Dawley rats. At the end of an extended period of repeated testing, tetrads of these two strains, as well as some selected Wistar tetrads, were tested in the elevated zero-maze and plasma corticosterone levels were determined. The differentiation in competition-performance among cage mates was not paralleled by a difference in performance in the elevated zero-maze or in plasma corticosterone levels in any of the three strains. These data indicate that the level of anxiety in a non-social paradigm, the elevated zero-maze, does not reflect the competition-performance within the home cage and thus, the dominant/subordinate status in this food-competition paradigm may not reflect/being caused by different levels of anxiety." @default.
- W2036869229 created "2016-06-24" @default.
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- W2036869229 date "2006-04-01" @default.
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- W2036869229 title "Competition for sucrose pellets in tetrads of male Wistar, Fischer or Sprague–Dawley rats: Is intra-group ranking reflected in the level of anxiety?" @default.
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- W2036869229 doi "https://doi.org/10.1016/j.bbr.2005.11.012" @default.
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