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• W2036870924 abstract "El tratamiento con bomba infusora de insulina trata de mejorar el control glucémico y disminuir el riesgo de hipoglucemia en diabetes tipo 1. Valorar las concentraciones de glucosa intersticial y la duración y los síntomas de las hipoglucemias e hiperglucemias con el uso de un monitor continuo de glucosa en niños y adolescentes con diabetes mellitus tipo 1 tratados con infusión de insulina, así como la tolerancia de esta prueba en estos pacientes. Se estudia a 13 pacientes (4 varones) con diabetes mellitus tipo 1 tratados con infusor de insulina, edad 10,6 ± 3,5 (intervalo, 3,2-13,6) años; tiempo de evolución de la diabetes mellitus, 5,0 ± 3,2 años; tiempo de tratamiento con bomba, 12,0 ± 4,6 meses; dosis de insulina, 0,99 ± 0,19 U/kg/día, y último valor de glucohemoglobina, 7,1 ± 0,8. Se utilizó el sistema CGMS de Minimed durante 72 h. El sensor no fue tolerado por el niño preescolar de 3 años. La concentración de glucosa intersticial captada por el sensor fue 187 ± 40 mg/dl. El tiempo en hipoglucemia (menor de 70 mg/dl) fue del 3,6% ± 5,6% del total y el tiempo en hiperglucemia (mayor de 180 mg/dl) fue del 47,3% ± 17,4% del total. En ningún caso se detectaron hipoglucemias subclínicas. Los niños y adolescentes con infusor de insulina muestran un perfil de glucosa intersticial muy irregular y no consiguen la normoglucemia. Nuestros pacientes conservan la sintomatología de alarma frente a la hipoglucemia y en general toleran bien el CGMS. Insulin pump therapy aims to improve glycemic control and decrease the risk of hypoglycemia in type 1 diabetes. To evaluate interstitial glucose levels and the frequency, duration and symptoms of hypo- and hyperglycemia through the use of a continuous glucose monitoring system (GGMS) in children and adolescents with insulin pump-treated type 1 diabetes, and to determine whether this monitoring method is well tolerated by these patients. Thirteen patients (4 boys) with insulin pump-treated type 1 diabetes mellitus were monitored. Age was 10.6 ± 3.5 (range, 3.2-13.6) years, diabetes duration was 5.0 ± 3.2 years, pump therapy duration was 12.0 ± 4.6 months, insulin dose was 0.99 ± 0.19 U/kg/day, and last hemoglobin A1c level was 7.1% ± 0.8%. The Minimed CGMS was used for 72 hours. A 3-year-old preschool child did not tolerate the CGMS. Interstitial glucose concentration was 187 ± 40 mg/dl. Hypoglycemia (below 70 mg/dl) accounted for 3.6% ± 5.6% of total time, while hyperglycemia (above 180 mg/dl) occurred 47.3% ± 17.4% of the time. No asymptomatic hypoglycemia episodes were detected. Insulin pump-treated children and adolescents showed an irregular interstitial glucose level and did not achieve normoglycemia. In our patients, adrenergic symptoms of hypoglycemia were preserved and the CGMS was generally well tolerated." @default.
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• W2036870924 date "2008-06-01" @default.
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• W2036870924 title "Monitorización continua de glucosa en niños tratados con bomba de insulina" @default.
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