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• W2036930891 abstract "You have accessJournal of UrologyAdrenal1 Apr 2015PD3-06 IMPACT OF PRIMARY HISTOLOGY ON DISEASE FREE SURVIVAL AFTER MINIMALLY INVASIVE ADRENALECTOMY FOR METASTATIC CANCER Mariaconsiglia Ferriero, Giuseppe Simone, Rocco Papalia, Riccardo Mastroianni, Salvatore Guaglianone, and Michele Gallucci Mariaconsiglia FerrieroMariaconsiglia Ferriero More articles by this author , Giuseppe SimoneGiuseppe Simone More articles by this author , Rocco PapaliaRocco Papalia More articles by this author , Riccardo MastroianniRiccardo Mastroianni More articles by this author , Salvatore GuaglianoneSalvatore Guaglianone More articles by this author , and Michele GallucciMichele Gallucci More articles by this author View All Author Informationhttps://doi.org/10.1016/j.juro.2015.02.293AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookTwitterLinked InEmail INTRODUCTION AND OBJECTIVES The adrenal gland is a site of metastasis for several malignancies. Metastasectomy with the achievement of a no evidence of disease (NED) status demonstrated to positively impact the oncological outcome. We report oncological results of a single centre 10-year experience with minimally invasive adrenalectomy for isolated adrenal metastasis. METHODS From May 2004 to May 2014, 162 patients underwent laparoscopic or robotic adrenalectomy. Pathological examination showed a metastasis in 36 patients. Baseline demographics, perioperative and follow up data were prospectively collected. Univariable and multivariable cox regression analyses were performed to identify predictors of disease free survival (DFS). RESULTS Median follow up was 28 months. Tumor histology was renal cell carcinoma (RCC) in 27 patients (75%). (Table 1) At univariable analysis bilateral adrenalectomy and primary tumor histology were predictors of DFS (p=0.048 and p=0.003, respectively). At multivariable cox analysis the only independent predictor of DFS was primary tumor histology (p=0.008). Lung cancer displayed similar DFS compared to RCC (reference category), while colon cancer (p=0.021; HR 7.08 [95% CI 0.96-1.28]), bladder cancer (p=0.001; HR102.6 [95% CI 7.3-1440]) and melanoma (p=0.01; HR 26.3 [95% CI 2.17-319], were significantly associated with worse outcomes. CONCLUSIONS Oncologic outcomes after adrenalectomy for metastatic cancer mainly depends on the primary tumor histology. Data Mean (SD) Age 56 (25) Side Right 14 (38.8) Left 16 (44.4) Bilateral 6 (16.8) Histology RCC 27 (75) Lung 4 (11.1) Bladder 2 (5.5) Colon 2 (5.5) Melanoma 1 (2.7) Adrenal size (cm) 6.2 (2.7) Tumor size (cm) 5.4 (2.9) © 2015 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 193Issue 4SApril 2015Page: e83 Advertisement Copyright & Permissions© 2015 by American Urological Association Education and Research, Inc.MetricsAuthor Information Mariaconsiglia Ferriero More articles by this author Giuseppe Simone More articles by this author Rocco Papalia More articles by this author Riccardo Mastroianni More articles by this author Salvatore Guaglianone More articles by this author Michele Gallucci More articles by this author Expand All Advertisement Advertisement PDF downloadLoading ..." @default.
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• W2036930891 title "PD3-06 IMPACT OF PRIMARY HISTOLOGY ON DISEASE FREE SURVIVAL AFTER MINIMALLY INVASIVE ADRENALECTOMY FOR METASTATIC CANCER" @default.
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