FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2036937573> ?p ?o ?g. }

• W2036937573 endingPage "668" @default.
• W2036937573 startingPage "655" @default.
• W2036937573 abstract "Previously, the GRF-INTERACTING FACTOR1 (GIF1)/ANGUSTIFOLIA3 (AN3) transcription coactivator gene, a member of a small gene family comprising three genes, was characterized as a positive regulator of cell proliferation in lateral organs, such as leaves and flowers, of Arabidopsis (Arabidopsis thaliana). As yet, it remains unclear how GIF1/AN3 affects the cell proliferation process. In this study, we demonstrate that the other members of the GIF gene family, GIF2 and GIF3, are also required for cell proliferation and lateral organ growth, as gif1, gif2, and gif3 mutations cause a synergistic reduction in cell numbers, leading to small lateral organs. Furthermore, GIF1, GIF2, and GIF3 overexpression complemented a cell proliferation defect of the gif1 mutant and significantly increased lateral organ growth of wild-type plants as well, indicating that members of the GIF gene family are functionally redundant. Kinematic analysis on leaf growth revealed that the gif triple mutant as well as other strong gif mutants developed leaf primordia with fewer cells, which was due to the low rate of cell proliferation, eventually resulting in earlier exit from the proliferative phase of organ growth. The low proliferative activity of primordial leaves was accompanied by decreased expression of cell cycle-regulating genes, indicating that GIF genes may act upstream of cell cycle regulators. Analysis of gif double and triple mutants clarified a previously undescribed role of the GIF gene family: gif mutants had small vegetative shoot apical meristems, which was correlated with the development of small leaf primordia. gif triple mutants also displayed defective structures of floral organs. Taken together, our results suggest that the GIF gene family plays important roles in the control of cell proliferation via cell cycle regulation and in other developmental properties that are associated with shoot apical meristem function." @default.
• W2036937573 created "2016-06-24" @default.
• W2036937573 creator A5004786915 @default.
• W2036937573 creator A5019170593 @default.
• W2036937573 creator A5024922818 @default.
• W2036937573 creator A5035350196 @default.
• W2036937573 creator A5048233009 @default.
• W2036937573 creator A5083254518 @default.
• W2036937573 date "2009-07-31" @default.
• W2036937573 modified "2023-10-16" @default.
• W2036937573 title "The Arabidopsis <i>GRF-INTERACTING FACTOR</i> Gene Family Performs an Overlapping Function in Determining Organ Size as Well as Multiple Developmental Properties " @default.
• W2036937573 cites W1581261221 @default.
• W2036937573 cites W1970207103 @default.
• W2036937573 cites W1970622479 @default.
• W2036937573 cites W1971429352 @default.
• W2036937573 cites W1980300422 @default.
• W2036937573 cites W1985508728 @default.
• W2036937573 cites W1996792476 @default.
• W2036937573 cites W2000345299 @default.
• W2036937573 cites W2013318939 @default.
• W2036937573 cites W2017541973 @default.
• W2036937573 cites W2029609262 @default.
• W2036937573 cites W2041795770 @default.
• W2036937573 cites W2042667559 @default.
• W2036937573 cites W2046846478 @default.
• W2036937573 cites W2047882742 @default.
• W2036937573 cites W2050179520 @default.
• W2036937573 cites W2051777213 @default.
• W2036937573 cites W2053427298 @default.
• W2036937573 cites W2056274750 @default.
• W2036937573 cites W2060166196 @default.
• W2036937573 cites W2060677459 @default.
• W2036937573 cites W2061280571 @default.
• W2036937573 cites W2065898768 @default.
• W2036937573 cites W2068245433 @default.
• W2036937573 cites W2070916915 @default.
• W2036937573 cites W2090978651 @default.
• W2036937573 cites W2097820884 @default.
• W2036937573 cites W2098115340 @default.
• W2036937573 cites W2106441153 @default.
• W2036937573 cites W2109980254 @default.
• W2036937573 cites W2115190641 @default.
• W2036937573 cites W2116122104 @default.
• W2036937573 cites W2116163614 @default.
• W2036937573 cites W2116168397 @default.
• W2036937573 cites W2121767306 @default.
• W2036937573 cites W2122732413 @default.
• W2036937573 cites W2129847122 @default.
• W2036937573 cites W2131597872 @default.
• W2036937573 cites W2135034679 @default.
• W2036937573 cites W2140057474 @default.
• W2036937573 cites W2143142471 @default.
• W2036937573 cites W2146365390 @default.
• W2036937573 cites W2150592964 @default.
• W2036937573 cites W2151626768 @default.
• W2036937573 cites W2157078388 @default.
• W2036937573 cites W2160283348 @default.
• W2036937573 cites W2161091137 @default.
• W2036937573 cites W2162605206 @default.
• W2036937573 cites W2165932947 @default.
• W2036937573 cites W2171198297 @default.
• W2036937573 cites W2184887719 @default.
• W2036937573 cites W2186112563 @default.
• W2036937573 doi "https://doi.org/10.1104/pp.109.141838" @default.
• W2036937573 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2754652" @default.
• W2036937573 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19648231" @default.
• W2036937573 hasPublicationYear "2009" @default.
• W2036937573 type Work @default.
• W2036937573 sameAs 2036937573 @default.
• W2036937573 citedByCount "174" @default.
• W2036937573 countsByYear W20369375732012 @default.
• W2036937573 countsByYear W20369375732013 @default.
• W2036937573 countsByYear W20369375732014 @default.
• W2036937573 countsByYear W20369375732015 @default.
• W2036937573 countsByYear W20369375732016 @default.
• W2036937573 countsByYear W20369375732017 @default.
• W2036937573 countsByYear W20369375732018 @default.
• W2036937573 countsByYear W20369375732019 @default.
• W2036937573 countsByYear W20369375732020 @default.
• W2036937573 countsByYear W20369375732021 @default.
• W2036937573 countsByYear W20369375732022 @default.
• W2036937573 countsByYear W20369375732023 @default.
• W2036937573 crossrefType "journal-article" @default.
• W2036937573 hasAuthorship W2036937573A5004786915 @default.
• W2036937573 hasAuthorship W2036937573A5019170593 @default.
• W2036937573 hasAuthorship W2036937573A5024922818 @default.
• W2036937573 hasAuthorship W2036937573A5035350196 @default.
• W2036937573 hasAuthorship W2036937573A5048233009 @default.
• W2036937573 hasAuthorship W2036937573A5083254518 @default.
• W2036937573 hasBestOaLocation W20369375732 @default.
• W2036937573 hasConcept C104317684 @default.
• W2036937573 hasConcept C126021549 @default.
• W2036937573 hasConcept C143065580 @default.
• W2036937573 hasConcept C150194340 @default.
• W2036937573 hasConcept C184750944 @default.
• W2036937573 hasConcept C2775988993 @default.
• W2036937573 hasConcept C2779491563 @default.
• W2036937573 hasConcept C54355233 @default.

• next