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Matches in SemOpenAlex for { <https://semopenalex.org/work/W2036954205> ?p ?o ?g. }

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• W2036954205 startingPage "7583" @default.
• W2036954205 abstract "Kinesin spindle protein (KSP), a member of the kinesin superfamily of microtubule-based motors, plays a critical role in mitosis as it mediates centrosome separation and bipolar spindle assembly and maintenance. Inhibition of KSP function leads to cell cycle arrest at mitosis with the formation of monoastral microtubule arrays, and ultimately, to cell death. Several KSP inhibitors are currently being studied in clinical trials and provide new opportunities for the development of novel anticancer therapeutics alternative from the available microtubule targeting drugs." @default.
• W2036954205 created "2016-06-24" @default.
• W2036954205 creator A5027923722 @default.
• W2036954205 creator A5050628777 @default.
• W2036954205 date "2008-12-01" @default.
• W2036954205 modified "2023-10-12" @default.
• W2036954205 title "Targeting the Kinesin Spindle Protein: Basic Principles and Clinical Implications" @default.
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• W2036954205 doi "https://doi.org/10.1158/1078-0432.ccr-08-0120" @default.
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