FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2036961315> ?p ?o ?g. }

• W2036961315 endingPage "2674" @default.
• W2036961315 startingPage "2669" @default.
• W2036961315 abstract "Increasing use of transgenic and gene targeting techniques for the investigation of hemostasis and vascular biology has generated interest in experimental models of carotid artery thrombosis in mice.We tested the hypothesis that hypoventilation in anesthetized mice may cause hypercapnia, increased carotid artery blood flow, and altered thrombotic responses to photochemical injury of the carotid artery.Arterial blood gases and carotid artery blood flow were measured in pentobarbital-anesthetized BALB/c or C57BL/6 J mice with and without mechanical ventilation. Photochemical injury of the carotid artery was induced using the rose bengal method.Compared with ventilated mice, unventilated mice had a 45% increase in carotid artery blood flow (0.74 +/- 0.04 vs. 0.41 +/- 0.03 mL min-1; P < 0.001) that was associated with an elevation of arterial PCO2 (58 +/- 4 vs. 33 +/- 4 mmHg; P < 0.05) and a decrease in arterial pH (7.18 +/- 0.05 vs. 7.32 +/- 0.03; P < 0.05). Time to first occlusion of the carotid artery after photochemical injury was shorter in ventilated than in unventilated mice (29 +/- 6 vs. 73 +/- 9 min; P < 0.001). Time to stable occlusion was also shorter in ventilated mice (49 +/- 8 vs. 81 +/- 6 min; P < 0.05). Elevated carotid artery blood flow, hypercarbic acidosis, and prolonged occlusion times also were observed in mice ventilated with supplemental carbon dioxide.General anesthesia without mechanical ventilation has the potential to confound studies of experimental thrombosis in vivo by producing hypoventilation, hypercapnia, acidosis, and altered carotid artery blood flow. Mechanical ventilation with maintenance of normal blood gases may enhance the physiological insight gained from experimental models of carotid artery thrombosis in mice." @default.
• W2036961315 created "2016-06-24" @default.
• W2036961315 creator A5005050920 @default.
• W2036961315 creator A5018923224 @default.
• W2036961315 creator A5055453699 @default.
• W2036961315 creator A5070640404 @default.
• W2036961315 date "2003-12-01" @default.
• W2036961315 modified "2023-10-07" @default.
• W2036961315 title "Effect of mechanical ventilation on carotid artery thrombosis induced by photochemical injury in mice" @default.
• W2036961315 cites W15890236 @default.
• W2036961315 cites W164687564 @default.
• W2036961315 cites W1841248941 @default.
• W2036961315 cites W1964335384 @default.
• W2036961315 cites W1998452524 @default.
• W2036961315 cites W2017697286 @default.
• W2036961315 cites W2039909869 @default.
• W2036961315 cites W2054192169 @default.
• W2036961315 cites W2075712620 @default.
• W2036961315 cites W2090858727 @default.
• W2036961315 cites W2119956225 @default.
• W2036961315 cites W2126780507 @default.
• W2036961315 cites W2136786502 @default.
• W2036961315 cites W2146908291 @default.
• W2036961315 cites W2416627159 @default.
• W2036961315 cites W2416980172 @default.
• W2036961315 cites W4240067294 @default.
• W2036961315 doi "https://doi.org/10.1111/j.1538-7836.2003.00482.x" @default.
• W2036961315 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/14675104" @default.
• W2036961315 hasPublicationYear "2003" @default.
• W2036961315 type Work @default.
• W2036961315 sameAs 2036961315 @default.
• W2036961315 citedByCount "28" @default.
• W2036961315 countsByYear W20369613152012 @default.
• W2036961315 countsByYear W20369613152013 @default.
• W2036961315 countsByYear W20369613152014 @default.
• W2036961315 countsByYear W20369613152015 @default.
• W2036961315 countsByYear W20369613152016 @default.
• W2036961315 countsByYear W20369613152017 @default.
• W2036961315 countsByYear W20369613152018 @default.
• W2036961315 countsByYear W20369613152019 @default.
• W2036961315 countsByYear W20369613152023 @default.
• W2036961315 crossrefType "journal-article" @default.
• W2036961315 hasAuthorship W2036961315A5005050920 @default.
• W2036961315 hasAuthorship W2036961315A5018923224 @default.
• W2036961315 hasAuthorship W2036961315A5055453699 @default.
• W2036961315 hasAuthorship W2036961315A5070640404 @default.
• W2036961315 hasBestOaLocation W20369613151 @default.
• W2036961315 hasConcept C126322002 @default.
• W2036961315 hasConcept C127413603 @default.
• W2036961315 hasConcept C158846371 @default.
• W2036961315 hasConcept C164705383 @default.
• W2036961315 hasConcept C200457457 @default.
• W2036961315 hasConcept C2776820930 @default.
• W2036961315 hasConcept C2777037550 @default.
• W2036961315 hasConcept C2777080012 @default.
• W2036961315 hasConcept C2778553927 @default.
• W2036961315 hasConcept C2779537118 @default.
• W2036961315 hasConcept C2779594553 @default.
• W2036961315 hasConcept C2780868729 @default.
• W2036961315 hasConcept C2781064879 @default.
• W2036961315 hasConcept C2987047532 @default.
• W2036961315 hasConcept C42219234 @default.
• W2036961315 hasConcept C534529494 @default.
• W2036961315 hasConcept C71924100 @default.
• W2036961315 hasConcept C78519656 @default.
• W2036961315 hasConceptScore W2036961315C126322002 @default.
• W2036961315 hasConceptScore W2036961315C127413603 @default.
• W2036961315 hasConceptScore W2036961315C158846371 @default.
• W2036961315 hasConceptScore W2036961315C164705383 @default.
• W2036961315 hasConceptScore W2036961315C200457457 @default.
• W2036961315 hasConceptScore W2036961315C2776820930 @default.
• W2036961315 hasConceptScore W2036961315C2777037550 @default.
• W2036961315 hasConceptScore W2036961315C2777080012 @default.
• W2036961315 hasConceptScore W2036961315C2778553927 @default.
• W2036961315 hasConceptScore W2036961315C2779537118 @default.
• W2036961315 hasConceptScore W2036961315C2779594553 @default.
• W2036961315 hasConceptScore W2036961315C2780868729 @default.
• W2036961315 hasConceptScore W2036961315C2781064879 @default.
• W2036961315 hasConceptScore W2036961315C2987047532 @default.
• W2036961315 hasConceptScore W2036961315C42219234 @default.
• W2036961315 hasConceptScore W2036961315C534529494 @default.
• W2036961315 hasConceptScore W2036961315C71924100 @default.
• W2036961315 hasConceptScore W2036961315C78519656 @default.
• W2036961315 hasIssue "12" @default.
• W2036961315 hasLocation W20369613151 @default.
• W2036961315 hasLocation W20369613152 @default.
• W2036961315 hasOpenAccess W2036961315 @default.
• W2036961315 hasPrimaryLocation W20369613151 @default.
• W2036961315 hasRelatedWork W1978291239 @default.
• W2036961315 hasRelatedWork W1982433963 @default.
• W2036961315 hasRelatedWork W2047567570 @default.
• W2036961315 hasRelatedWork W2080971734 @default.
• W2036961315 hasRelatedWork W2109518198 @default.
• W2036961315 hasRelatedWork W2157990214 @default.
• W2036961315 hasRelatedWork W2433989503 @default.
• W2036961315 hasRelatedWork W2497785827 @default.
• W2036961315 hasRelatedWork W3090738329 @default.
• W2036961315 hasRelatedWork W4252994144 @default.

• next