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• W2037019211 abstract "Respiratory tract involvement is common in adults with systemic lupus erythematosus (SLE). Although SLE in children usually follows a more severe course than in adults, there are few reports on pulmonary disease and lung function in children with SLE. We performed lung function tests and chest x ray examinations in eight children with SLE (mean age 11.1 years), three of whom presented with pulmonary symptoms. A high prevalence of lung involvement was found, including interstitial or localised infiltrations, pleural effusion, a restrictive impairment of lung function, and dysfunction of the diaphragm. Three patients required artificial ventilation. Two main mechanisms of ventilatory impairment seem to occur in children with SLE: firstly, acute interstitial pneumonia, which rapidly improves on treatment with steroids, and, secondly, restriction of lung volume, mainly due to respiratory muscle weakness." @default.
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• W2037019211 date "1986-05-01" @default.
• W2037019211 modified "2023-09-27" @default.
• W2037019211 title "Respiratory tract disease in systemic lupus erythematosus." @default.
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• W2037019211 doi "https://doi.org/10.1136/adc.61.5.478" @default.
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