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- W2037076351 abstract "Our study aimed at examining the possible anti-inflammatory and antinociceptive effects of dantrolene sodium in rats and mice. The anti-inflammatory effect of dantrolene sodium (2.5, 5 and 10 mg kg (-1)) was investigated and compared with diclofenac sodium (5 mg kg (-1)) using the formalin-, histamine-, and carrageenan-induced paw oedema and cotton pellet granuloma tests. Analgesic effects of dantrolene sodium were evaluated and compared with metamizol (200 mg kg (-1)) in acetic acid-induced writhing and formalin-induced paw licking tests. It was found that dantrolene sodium significantly diminished the nociceptive response in mice, showing at the same time considerable anti-inflammatory properties in rats." @default.
- W2037076351 created "2016-06-24" @default.
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- W2037076351 date "2002-06-01" @default.
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- W2037076351 title "Anti-inflammatory and antinociceptive properties of dantrolene sodium in rats and mice" @default.
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- W2037076351 doi "https://doi.org/10.1006/phrs.2002.0970" @default.
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