Matches in SemOpenAlex for { <https://semopenalex.org/work/W2037088225> ?p ?o ?g. }
Showing items 1 to 92 of
92
with 100 items per page.
- W2037088225 endingPage "53" @default.
- W2037088225 startingPage "49" @default.
- W2037088225 abstract "The pharmacological characteristics of a pre-junctional 5-HT autoreceptor have been studied by following the Ca2+-dependent, K+-evoked release of [3H]-5-HT from preloaded rat frontal cortex slices. Added 5-HT, in the presence of the 5-HT uptake inhibitor chlorimipramine, caused a dose related inhibition of the K+-evoked release of [3H]-5-HT in this system as did the 5-HT analogues 5-methoxytryptamine, N-methyltryptamine, 5-methoxy-NN'-dimethyltryptamine, N-methyl 5-hydroxytryptamine and tryptamine. The inhibitory effect of 1 microM 5-HT on the K+-evoked release of [3H]-5-HT was reversed in a dose-related manner by the 5-HT antagonist drug, methiothepin (pA10 value 6.7). At a concentration of 1 microM, the 5-HT antagonists drugs cinanserin and mianserin produced a small but significant reversal of the 5-HT induced inhibition of K+-evoked [3H]-5-HT release, but methysergide, metergoline and cyproheptadine were completely without effect at this concentration. The results are interpreted as evidence for a pre-junctional autoreceptor for 5-HT in the frontal cortex of the rat with a different pharmacological specificity for 5-HT antagonists from previously studied 5-HT receptors." @default.
- W2037088225 created "2016-06-24" @default.
- W2037088225 creator A5022674193 @default.
- W2037088225 creator A5027751264 @default.
- W2037088225 creator A5054472152 @default.
- W2037088225 creator A5088028537 @default.
- W2037088225 creator A5091525006 @default.
- W2037088225 date "1982-01-01" @default.
- W2037088225 modified "2023-10-18" @default.
- W2037088225 title "K+-evoked [3H]-5-HT release from rat frontal cortex slices: the effect of 5-HT agonists and antagonists" @default.
- W2037088225 cites W1488521817 @default.
- W2037088225 cites W1986039293 @default.
- W2037088225 cites W2021333775 @default.
- W2037088225 cites W2022769542 @default.
- W2037088225 cites W2052325698 @default.
- W2037088225 cites W2054131131 @default.
- W2037088225 cites W2066607176 @default.
- W2037088225 cites W2067363410 @default.
- W2037088225 cites W2090580479 @default.
- W2037088225 doi "https://doi.org/10.1016/0006-2952(82)90234-9" @default.
- W2037088225 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7059349" @default.
- W2037088225 hasPublicationYear "1982" @default.
- W2037088225 type Work @default.
- W2037088225 sameAs 2037088225 @default.
- W2037088225 citedByCount "39" @default.
- W2037088225 countsByYear W20370882252020 @default.
- W2037088225 crossrefType "journal-article" @default.
- W2037088225 hasAuthorship W2037088225A5022674193 @default.
- W2037088225 hasAuthorship W2037088225A5027751264 @default.
- W2037088225 hasAuthorship W2037088225A5054472152 @default.
- W2037088225 hasAuthorship W2037088225A5088028537 @default.
- W2037088225 hasAuthorship W2037088225A5091525006 @default.
- W2037088225 hasConcept C126322002 @default.
- W2037088225 hasConcept C134018914 @default.
- W2037088225 hasConcept C170493617 @default.
- W2037088225 hasConcept C185592680 @default.
- W2037088225 hasConcept C2775864247 @default.
- W2037088225 hasConcept C2776120623 @default.
- W2037088225 hasConcept C2776885963 @default.
- W2037088225 hasConcept C2777095659 @default.
- W2037088225 hasConcept C2778206117 @default.
- W2037088225 hasConcept C2778258207 @default.
- W2037088225 hasConcept C2778938600 @default.
- W2037088225 hasConcept C2780831388 @default.
- W2037088225 hasConcept C2781005078 @default.
- W2037088225 hasConcept C53910766 @default.
- W2037088225 hasConcept C55493867 @default.
- W2037088225 hasConcept C71924100 @default.
- W2037088225 hasConcept C8439214 @default.
- W2037088225 hasConcept C86803240 @default.
- W2037088225 hasConcept C98274493 @default.
- W2037088225 hasConceptScore W2037088225C126322002 @default.
- W2037088225 hasConceptScore W2037088225C134018914 @default.
- W2037088225 hasConceptScore W2037088225C170493617 @default.
- W2037088225 hasConceptScore W2037088225C185592680 @default.
- W2037088225 hasConceptScore W2037088225C2775864247 @default.
- W2037088225 hasConceptScore W2037088225C2776120623 @default.
- W2037088225 hasConceptScore W2037088225C2776885963 @default.
- W2037088225 hasConceptScore W2037088225C2777095659 @default.
- W2037088225 hasConceptScore W2037088225C2778206117 @default.
- W2037088225 hasConceptScore W2037088225C2778258207 @default.
- W2037088225 hasConceptScore W2037088225C2778938600 @default.
- W2037088225 hasConceptScore W2037088225C2780831388 @default.
- W2037088225 hasConceptScore W2037088225C2781005078 @default.
- W2037088225 hasConceptScore W2037088225C53910766 @default.
- W2037088225 hasConceptScore W2037088225C55493867 @default.
- W2037088225 hasConceptScore W2037088225C71924100 @default.
- W2037088225 hasConceptScore W2037088225C8439214 @default.
- W2037088225 hasConceptScore W2037088225C86803240 @default.
- W2037088225 hasConceptScore W2037088225C98274493 @default.
- W2037088225 hasIssue "1" @default.
- W2037088225 hasLocation W20370882251 @default.
- W2037088225 hasLocation W20370882252 @default.
- W2037088225 hasOpenAccess W2037088225 @default.
- W2037088225 hasPrimaryLocation W20370882251 @default.
- W2037088225 hasRelatedWork W1989049022 @default.
- W2037088225 hasRelatedWork W1998389816 @default.
- W2037088225 hasRelatedWork W2010375930 @default.
- W2037088225 hasRelatedWork W2033350616 @default.
- W2037088225 hasRelatedWork W2034328800 @default.
- W2037088225 hasRelatedWork W2037088225 @default.
- W2037088225 hasRelatedWork W2037109444 @default.
- W2037088225 hasRelatedWork W2054184534 @default.
- W2037088225 hasRelatedWork W2084967960 @default.
- W2037088225 hasRelatedWork W2425592638 @default.
- W2037088225 hasVolume "31" @default.
- W2037088225 isParatext "false" @default.
- W2037088225 isRetracted "false" @default.
- W2037088225 magId "2037088225" @default.
- W2037088225 workType "article" @default.