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- W2037112143 abstract "To assess the effect of chronic deconditioning on cardiac dimensions and function in subjects with high-level spinal cord injury (SCI), who represent a human in-vivo model of extreme inactivity.Cross-sectional study.University medical center.Seven men with tetraplegia and 7 able-bodied controls.Not applicable.Echocardiographic measurements of resting cardiac dimensions, systolic function, and global and long-axis diastolic function.Left ventricular mass index was significantly lower in the subjects with SCI than in the controls (90.8+/-26 g/m(2) vs 122+/-28.9 g/m(2); P=.05). In addition, dimensions of left ventricle, left atrium, and vena cava inferior were all significantly reduced in the subjects with SCI compared with controls (P<.05). There were no differences between the groups for any of the parameters reflecting systolic and global and long-axis diastolic function.Tetraplegia is associated with a reduction in cardiac mass and dimensions. Resting diastolic and systolic function is not altered with continued exposure to inactivity, however, which suggests a remodeling of the heart as a physiologic adaptive process." @default.
- W2037112143 created "2016-06-24" @default.
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- W2037112143 date "2006-09-01" @default.
- W2037112143 modified "2023-10-16" @default.
- W2037112143 title "Preserved Cardiac Function After Chronic Spinal Cord Injury" @default.
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- W2037112143 doi "https://doi.org/10.1016/j.apmr.2006.05.023" @default.
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