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- W2037112190 abstract "This FOCIS Centers of Excellence Short Analytical Review is based on the clinical vignette of two boys from the same family with very different outcomes following hematopoietic stem cell transplantation (HSCT) for X-linked severe combined immunodeficiency (SCID). We review the kinetics of immune reconstitution following HSCT in SCID and emphasize the latest information regarding optimizing transplant outcomes for this disorder. The cases illustrate the difficulties and controversies surrounding the optimal strategies for planning SCID transplants. Specifically, we will focus on 3 areas of current debate and investigation: (i) factors involved in donor selection; (ii) the role of pretransplant conditioning; and (iii) benefits of early HSCT for SCID." @default.
- W2037112190 created "2016-06-24" @default.
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- W2037112190 date "2009-05-01" @default.
- W2037112190 modified "2023-10-16" @default.
- W2037112190 title "Optimizing outcomes of hematopoietic stem cell transplantation for severe combined immunodeficiency" @default.
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- W2037112190 doi "https://doi.org/10.1016/j.clim.2009.01.003" @default.
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