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- W2037122768 abstract "Nodularin (NODLN) is a cyclic pentapeptide hepatotoxin produced by the cyanobacterium Nodularia spumigena, which forms extensive blooms during the summer in the Baltic Sea. Nodularin was detected in liver, muscle and/or feather samples of several common eiders (Somateria mollissima) from the Gulf of Finland (northern Baltic Sea) in 2002–2005. Published information on the adverse effects of NODLN in marine birds is scarce. The aim of this study was to evaluate the toxicity of NODLN, and determine the concentrations of NODLN in liver and muscle tissue in mallards (Anas platyrhynchos) exposed to N. spumigena. Mallards received a single or multiple exposure via oral gavage with an aqueous slurry containing toxic N. spumigena. Dosages ranged from 200 to 600 µg NODLN per kg body weight (bw). There were minimal histopathological changes in liver tissue, and brain cholinesterase activity did not differ among treatment groups. Concentrations of NODLN measured by LC-MS in liver varied between approximately 3–120 µg..." @default.
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- W2037122768 date "2008-05-01" @default.
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- W2037122768 title "Exposure of mallards (<b><i>Anas platyrhynchos</i></b>) to the hepatotoxic cyanobacterium<b><i>Nodularia spumigena</i></b>" @default.
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- W2037122768 doi "https://doi.org/10.1080/02772240701529103" @default.
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