Matches in SemOpenAlex for { <https://semopenalex.org/work/W2037133034> ?p ?o ?g. }
- W2037133034 endingPage "463" @default.
- W2037133034 startingPage "459" @default.
- W2037133034 abstract "A case-control survey of 48 children with nonsyndromic cleft lip or palate showed a significant increase in prevalence of maternal use of topical corticosteroid preparations in the first trimester of pregnancy, compared to 58 controls born in the same hospital; the odds ratio was 13.154, 95% confidence interval 1.67-586, P = 0.0049 on Fisher's exact two-tail test. The results were statistically significant although the wide confidence interval reflected the small sample size. Although older epidemiological studies have not detected any association between systemic corticosteroid treatment and the combined incidence of all congenital malformations, experimental studies over several decades have shown that maternal corticosteroid exposure in several species of animals is specifically associated with oral clefts. This association has been confirmed by more specific case-control surveys where the cases were children with cleft lip or palate and the exposure was maternal systemic corticosteroid treatment in the first trimester. Only one previous survey also analyzed topical corticosteroids, and it demonstrated an increased odds ratio for cleft lip or palate. A national survey of children with cleft palate will be necessary to evaluate the results of this pilot study." @default.
- W2037133034 created "2016-06-24" @default.
- W2037133034 creator A5004703547 @default.
- W2037133034 creator A5005986035 @default.
- W2037133034 creator A5042889006 @default.
- W2037133034 creator A5053331577 @default.
- W2037133034 creator A5077458187 @default.
- W2037133034 creator A5084169740 @default.
- W2037133034 creator A5089384499 @default.
- W2037133034 date "2003-07-22" @default.
- W2037133034 modified "2023-10-14" @default.
- W2037133034 title "Case-control study of cleft lip or palate after maternal use of topical corticosteroids during pregnancy" @default.
- W2037133034 cites W1513257145 @default.
- W2037133034 cites W155124885 @default.
- W2037133034 cites W1925939613 @default.
- W2037133034 cites W1971596431 @default.
- W2037133034 cites W1989065382 @default.
- W2037133034 cites W1991143002 @default.
- W2037133034 cites W1993956390 @default.
- W2037133034 cites W1995877613 @default.
- W2037133034 cites W1998109596 @default.
- W2037133034 cites W1998225732 @default.
- W2037133034 cites W2002273520 @default.
- W2037133034 cites W2002967400 @default.
- W2037133034 cites W2008094662 @default.
- W2037133034 cites W2012506172 @default.
- W2037133034 cites W2027834218 @default.
- W2037133034 cites W2029310537 @default.
- W2037133034 cites W2029466348 @default.
- W2037133034 cites W2035285899 @default.
- W2037133034 cites W2041134324 @default.
- W2037133034 cites W2048046716 @default.
- W2037133034 cites W2111163459 @default.
- W2037133034 cites W2135470023 @default.
- W2037133034 cites W2164071690 @default.
- W2037133034 cites W4236235450 @default.
- W2037133034 cites W4327634773 @default.
- W2037133034 cites W46695127 @default.
- W2037133034 doi "https://doi.org/10.1002/ajmg.a.20130" @default.
- W2037133034 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12884422" @default.
- W2037133034 hasPublicationYear "2003" @default.
- W2037133034 type Work @default.
- W2037133034 sameAs 2037133034 @default.
- W2037133034 citedByCount "72" @default.
- W2037133034 countsByYear W20371330342012 @default.
- W2037133034 countsByYear W20371330342013 @default.
- W2037133034 countsByYear W20371330342014 @default.
- W2037133034 countsByYear W20371330342015 @default.
- W2037133034 countsByYear W20371330342016 @default.
- W2037133034 countsByYear W20371330342017 @default.
- W2037133034 countsByYear W20371330342018 @default.
- W2037133034 countsByYear W20371330342019 @default.
- W2037133034 countsByYear W20371330342020 @default.
- W2037133034 countsByYear W20371330342021 @default.
- W2037133034 countsByYear W20371330342022 @default.
- W2037133034 countsByYear W20371330342023 @default.
- W2037133034 crossrefType "journal-article" @default.
- W2037133034 hasAuthorship W2037133034A5004703547 @default.
- W2037133034 hasAuthorship W2037133034A5005986035 @default.
- W2037133034 hasAuthorship W2037133034A5042889006 @default.
- W2037133034 hasAuthorship W2037133034A5053331577 @default.
- W2037133034 hasAuthorship W2037133034A5077458187 @default.
- W2037133034 hasAuthorship W2037133034A5084169740 @default.
- W2037133034 hasAuthorship W2037133034A5089384499 @default.
- W2037133034 hasConcept C107130276 @default.
- W2037133034 hasConcept C120665830 @default.
- W2037133034 hasConcept C121332964 @default.
- W2037133034 hasConcept C126322002 @default.
- W2037133034 hasConcept C131872663 @default.
- W2037133034 hasConcept C141071460 @default.
- W2037133034 hasConcept C146304588 @default.
- W2037133034 hasConcept C156957248 @default.
- W2037133034 hasConcept C187212893 @default.
- W2037133034 hasConcept C191093355 @default.
- W2037133034 hasConcept C199343813 @default.
- W2037133034 hasConcept C2776804153 @default.
- W2037133034 hasConcept C2779234561 @default.
- W2037133034 hasConcept C44249647 @default.
- W2037133034 hasConcept C54355233 @default.
- W2037133034 hasConcept C61511704 @default.
- W2037133034 hasConcept C71924100 @default.
- W2037133034 hasConcept C86803240 @default.
- W2037133034 hasConceptScore W2037133034C107130276 @default.
- W2037133034 hasConceptScore W2037133034C120665830 @default.
- W2037133034 hasConceptScore W2037133034C121332964 @default.
- W2037133034 hasConceptScore W2037133034C126322002 @default.
- W2037133034 hasConceptScore W2037133034C131872663 @default.
- W2037133034 hasConceptScore W2037133034C141071460 @default.
- W2037133034 hasConceptScore W2037133034C146304588 @default.
- W2037133034 hasConceptScore W2037133034C156957248 @default.
- W2037133034 hasConceptScore W2037133034C187212893 @default.
- W2037133034 hasConceptScore W2037133034C191093355 @default.
- W2037133034 hasConceptScore W2037133034C199343813 @default.
- W2037133034 hasConceptScore W2037133034C2776804153 @default.
- W2037133034 hasConceptScore W2037133034C2779234561 @default.
- W2037133034 hasConceptScore W2037133034C44249647 @default.
- W2037133034 hasConceptScore W2037133034C54355233 @default.
- W2037133034 hasConceptScore W2037133034C61511704 @default.